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Evaluation of estrogenic, antiestrogenic and genotoxic activity of nemorosone, the major compound found in brown Cuban propolis
ArticleAbstract: Background: Brown propolis is the major type of propolis found in Cuba; its principal component is nPalabras claves:Clusia rosea, Estrogenicity, genotoxicity, nemorosone, propolisAutores:Boldrin P., Camargo M.S., Cardoso C., Fernández M., Molina-Molina J., Olea N., Osmany Cuesta-Rubio, Prieto A., Resende F.A., Varanda E.A., Vilegas W.Fuentes:googlescopusEffects of nemorosone, isolated from the plant Clusia rosea, on the cell cycle and gene expression in MCF-7 BUS breast cancer cell lines
ArticleAbstract: Background: Breast cancer is the cause of considerable morbidity and mortality in women. While estroPalabras claves:Breast Cancer, cell cycle, Clusia rosea, Gene Expression, nemorosoneAutores:Camargo M.S., Espanha L., Nogueira C., Oliveira M., Oliveira-Höhne A., Osmany Cuesta-Rubio, Resende F.A., Santoni M., Varanda E.A., Vilegas W.Fuentes:scopusCuban brown propolis interferes in the crosstalk between colorectal cancer cells and m2 macrophages
ArticleAbstract: Tumor-associated macrophages (TAMs), primarily the M2 phenotype, are involved in the progression andPalabras claves:Colorectal cancer, Epithelial– mesenchymal transition, nemorosone, propolis, Tumor-associated macrophagesAutores:Carrara M., De Martin S., Frión-herrera Y., Gabbia D., Osmany Cuesta-Rubio, Scaffidi M., Zagni L.Fuentes:googlescopusA review of nemorosone: Chemistry and biological properties
ArticleAbstract: Nemorosone is a bicyclic polyprenylated acylphloroglucinol derivative originally isolated from ClusiPalabras claves:Acylphloroglucinols, Anti-Cancer, Clusiaceae, nemorosone, Pharmacological activityAutores:Fernández-Acosta R., Monzote L., Osmany Cuesta-Rubio, Pardo-Andreu G.L., Rastrelli L.Fuentes:googlescopusChemosensitizing activity of Cuban propolis and nemorosone in doxorubicin resistant human colon carcinoma cells
ArticleAbstract: Propolis is a natural product obtained from bees, used since ancient times for its multiple pharmacoPalabras claves:Chemosensitization, Colorectal cancer, Combination chemotherapy, nemorosone, propolisAutores:Carrara M., Díaz-García A., Frión-herrera Y., Gabbia D., Osmany Cuesta-RubioFuentes:googlescopusClusianone, a naturally occurring nemorosone regioisomer, uncouples rat liver mitochondria and induces HepG2 cell death
ArticleAbstract: Clusianone is a member of the polycyclic polyprenylated acylphloroglucinol family of natural productPalabras claves:Clusianone, HepG2 cell death, Mitochondria, nemorosone, Protonophore, UncouplerAutores:Alberici L.C., Curti C., Marín-Prida J., Núñez-Figueredo Y., Osmany Cuesta-Rubio, Pardo-Andreu G.L., Reis F.H.Z., Uyemura S.A.Fuentes:googlescopusAntimicrobial evaluation of the polyisoprenylated benzophenones nemorosone and guttiferone A
ArticleAbstract: Polyisoprenylated benzophenones have been isolated from plants, particularly in the Clusiaceae familPalabras claves:antibacterial, Antiprotozoal, guttiferone A, nemorosoneAutores:Cos P., Maes L., Matheeussen A., Monzote L., Osmany Cuesta-Rubio, Van Assche T.Fuentes:googlescopusAssessment of estrogenic, mutagenic and antimutagenic activity of nemorosone
ArticleAbstract: Currently, a wide range of research involving natural products is focused on the discovery of new drPalabras claves:Ames test, Antimutagenic activity, Estrogenic activity, nemorosoneAutores:Camargo M.S., de Oliveira A.P.S., Osmany Cuesta-Rubio, Resende F.A., Varanda E.A., Varela S.D., Vilegas W.Fuentes:scopusThe anti-cancer agent nemorosone is a new potent protonophoric mitochondrial uncoupler
ArticleAbstract: Nemorosone, a natural-occurring polycyclic polyprenylated acylphloroglucinol, has received increasinPalabras claves:Cáncer, HepG2 cell death, Mitochondria, nemorosone, Protonophore, UncouplerAutores:Alberici L.C., Curti C., Leopoldino A.M., Núñez-Figueredo Y., Osmany Cuesta-Rubio, Pardo-Andreu G.L., Pestana C.R., Rodrigues F.P., Tudella V.G., Uyemura S.A.Fuentes:googlescopusThe cuban propolis component nemorosone inhibits proliferation and metastatic properties of human colorectal cancer cells
ArticleAbstract: The majority of deaths related to colorectal cancer (CRC) are associated with the metastatic processPalabras claves:Apoptosis cell death, Colorectal cancer, Epithelial, Mesenchymal transition, nemorosone, propolisAutores:Carrara M., De Martin S., Frión-herrera Y., Gabbia D., Osmany Cuesta-Rubio, Scaffidi M., Zagni L.Fuentes:googlescopus