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Evaluation of estrogenic, antiestrogenic and genotoxic activity of nemorosone, the major compound found in brown Cuban propolis
ArticleAbstract: Background: Brown propolis is the major type of propolis found in Cuba; its principal component is nPalabras claves:Clusia rosea, Estrogenicity, genotoxicity, nemorosone, propolisAutores:Boldrin P., Camargo M.S., Cardoso C., Fernández M., Molina-Molina J., Olea N., Osmany Cuesta-Rubio, Prieto A., Resende F.A., Varanda E.A., Vilegas W.Fuentes:googlescopusFragmentation Pathways of Polycyclic Polyisoprenylated Benzophenones and Degradation Profile of Nemorosone by Multiple-Stage Tandem Mass Spectrometry
ArticleAbstract: Nemorosone is a polycyclic polyisoprenylated benzophenone (PPBs) with strong cytotoxic activity. ItPalabras claves:Autores:Campone L., Dal Piaz F., Osmany Cuesta-Rubio, Piccinelli L.A., Rastrelli L.Fuentes:googlescopusGC-MS determination of isoflavonoids in seven red cuban propolis samples
ArticleAbstract: In the present study, the phenolic composition analysis of seven red varieties of propolis, collectePalabras claves:GC-MS, Isoflavonoids, Pterocarpans, Red cuban propolisAutores:Ingrid Márquez-Hernández, Mercedes Campo Fernández, Montes de Oca Porto R., Osmany Cuesta-Rubio, Perez A.R., Piccinelli L.A., Rastrelli L.Fuentes:scopusConstituents of the Cuban endemic species Calophyllum pinetorum
ArticleAbstract: A new prenylated xanthone, pinetoxanthone (1), and two new pyranochromanones, pinetoric acid I (2) aPalabras claves:Autores:Bello Adonis Alarcón, Osmany Cuesta-Rubio, Pérez J.C., Piccinelli L.A., Rastrelli L.Fuentes:googlescopusEffects of nemorosone, isolated from the plant Clusia rosea, on the cell cycle and gene expression in MCF-7 BUS breast cancer cell lines
ArticleAbstract: Background: Breast cancer is the cause of considerable morbidity and mortality in women. While estroPalabras claves:Breast Cancer, cell cycle, Clusia rosea, Gene Expression, nemorosoneAutores:Camargo M.S., Espanha L., Nogueira C., Oliveira M., Oliveira-Höhne A., Osmany Cuesta-Rubio, Resende F.A., Santoni M., Varanda E.A., Vilegas W.Fuentes:scopusDetermination of biflavonoids in different parts of garcinia bakeriana (Urb) borhidi
ArticleAbstract: Introduction: Previous studies have revealed genus Garcinia to be a rich source of secondary metabolPalabras claves:Biflavonoids, Garcinia bakeriana, UPLCAutores:Al-Shaghdari A., Bello Adonis Alarcón, Osmany Cuesta-RubioFuentes:googlescopusDiscerning the antioxidant mechanism of rapanone: A naturally occurring benzoquinone with iron complexing and radical scavenging activities
ArticleAbstract: Oxidative stress resulting from iron and reactive oxygen species (ROS) homeostasis breakdown has beePalabras claves:antioxidant, Iron, Iron-chelation, Mitochondria, Quinones, RapanoneAutores:Antuch M., de la Vega-Hernández K., Núñez-Figueredo Y., Osmany Cuesta-Rubio, Pardo-Andreu G.L.Fuentes:googlescopusCuban and Brazilian red propolis: Botanical origin and comparative analysis by high-performance liquid chromatography-photodiode array detection/ electrospray ionization tandem mass spectrometry
ArticleAbstract: Chemical composition of propolis depends on the specificity of the local flora at the site of collecPalabras claves:Dalbergia ecastophyllum, Isoflavonoids, polyisoprenylated benzophenones, red propolis, retusapurpurin A and B, tandem mass spectrometryAutores:Campone L., Lotti C., Mercedes Campo Fernández, Osmany Cuesta-Rubio, Piccinelli L.A., Rastrelli L.Fuentes:scopusCuban brown propolis interferes in the crosstalk between colorectal cancer cells and m2 macrophages
ArticleAbstract: Tumor-associated macrophages (TAMs), primarily the M2 phenotype, are involved in the progression andPalabras claves:Colorectal cancer, Epithelial– mesenchymal transition, nemorosone, propolis, Tumor-associated macrophagesAutores:Carrara M., De Martin S., Frión-herrera Y., Gabbia D., Osmany Cuesta-Rubio, Scaffidi M., Zagni L.Fuentes:googlescopusA fast and efficient HPLC-PDA-MS method for detection and identification of pyranochromanone acids in Calophyllum species
ArticleAbstract: Pyranochromanone acids isolated from Calophyllum species have shown a variety of biological potentiaPalabras claves:1D and 2D NMR, Calophyllum antillanum leaves and resin, Calophyllum pinetorum leaves and resin, Calophyllumr rivulare leaves and resin, Pyranochromanone acidsAutores:Bello Adonis Alarcón, Kabani A., Lotti C., Osmany Cuesta-Rubio, Piccinelli L.A., Rastrelli L.Fuentes:googlescopus