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New chromene scaffolds for adenosine A<inf>2A</inf> receptors: Synthesis, pharmacology and structure-activity relationships
ArticleAbstract: In silico screening of a collection of 1584 academic compounds identified a small molecule hit for tPalabras claves:Adenosine receptors, Chromene scaffolds, G protein-coupled receptors, Knoevenagel condensation, Structure-activity relationshipAutores:Brea J., Castro M., Costa M., Filipe Miguel Areias, Gregori-Puigjané E., Loza M.I., Mestres J., Proença M.F.Fuentes:googlescopusPhenolic imidazole derivatives with dual antioxidant/antifungal activity: Synthesis and structure-activity relationship
ArticleAbstract: Background: Previous publications show that the addition of a phenolic antioxidant to an antifungalPalabras claves:Antifungal activity, Antioxidant activity, Cáncer, Phenolic imidazoles, Phenolic purines, Structure-activity relationshipAutores:Bettencourt A.P., Castro M., Coutinho O.P., Fernandes F., Filipe Miguel Areias, Proença M.F., Silva J.P., Sousa M.J.Fuentes:googlescopusSynthesis, binding affinity and SAR of new benzolactam derivatives as dopamine D<inf>3</inf> receptor ligands
ArticleAbstract: A series of new benzolactam derivatives was synthesized and the derivatives were evaluated for theirPalabras claves:antipsychotics, Arylpiperazines, Benzolactams, Dopamine receptors, Structure-activity relationshipAutores:Brea J., Filipe Miguel Areias, López L., Loza M.I., Masaguer C.F., Ortega R., Pastor M., Raviña E., Sanz F., Selent J.Fuentes:googlescopus