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Cell Penetrating Peptides as potential drug carriers
ReviewAbstract: The discovery and development of natural, synthetic or peptidomimetic cell-penetrating peptides (CPPPalabras claves:Blood-brain barrie, Cell penetrating peptides, Molecular transportes, PeptidesAutores:Alberício F., Hortensia Rodriguez Cabrera, Pulido X.C., Royo M.Fuentes:scopusEffect of thiadiazine derivatives on intracellular amastigotes of Leishmania amazonensis
ArticleAbstract: Current therapy for leishmaniasis is not satisfactory. We describe the in vitro antiproliferative efPalabras claves:AMASTIGOTES, LEISHMANIA, thiadiazineAutores:Álvarez A.M.M., Fidalgo L.M., Géigel L.F., Hortensia Rodriguez Cabrera, Navarro M.S., Pineiro R.P.Fuentes:googlescopusChemical Conjugation in Drug Delivery Systems
ReviewAbstract: Cancer is one of the diseases with the highest mortality rate. Treatments to mitigate cancer are usuPalabras claves:Biomolecules, Carriers, covalent bioconjugation, Drug delivery systems, linkersAutores:Alberício F., Alexis Eras, Danna Castillo, Hortensia Rodriguez Cabrera, Santiago Nelson Vispo, Suárez Navarro M.Fuentes:scopusAlkyl-linked bis-THTT derivatives as potent in vitro trypanocidal agents
ArticleAbstract: The effect of several alkyl-linked bis tetrahydro-(2H)-1,3,5-thiadiazine-2- thione (bis-THTT) on LeiPalabras claves:Alkyl-linked bis-THTT anti-protozoal activityAutores:Alvarez A., Atherton R., Coro J., Hortensia Rodriguez Cabrera, Little S., Perez-Pineiro R., Suárez Navarro M., Wharton H., Yardley V.Fuentes:googlescopusAn Androsterone-H<inf>2</inf>@C<inf>60</inf> hybrid: Synthesis, Properties and Molecular Docking Simulations with SARS-Cov-2
ArticleAbstract: We report the synthesis and characterization of a fullerene-steroid hybrid that contains H2@C60 andPalabras claves:cyclopropanation, Fullerenes, Molecular docking, SARS-COV-2, Steroid hybridsAutores:Alberício F., Almagro L., Herranz M.Á., Hortensia Rodriguez Cabrera, Lemos R., Makowski K., Maroto E., Martín N., Molero D., Murata Y., Ortiz O., Suárez Navarro M.Fuentes:scopusIn vitro and in vivo assays of 3,5-disubstituted-tetrahydro-2H-1,3,5-thiadiazin-2-thione derivatives against Trypanosoma cruzi
ArticleAbstract: Cytotoxicity assays of 24 new 3,5-disubstituted-tetrahydro-2H-1,3,5-thiadiazin-2-thione derivativesPalabras claves:AMASTIGOTES, Antichagasic drugs, Antitrypanosomal activity assays, Cytotoxicity assays, J774 macrophages, Thiadiazine thione derivativesAutores:García-Trevijano J.A.E., Gómez-Barrio A., Hortensia Rodriguez Cabrera, Muelas S., Ochoa C., Perez-Pineiro R., Suárez Navarro M.Fuentes:googlescopusThiadiazine derivatives as antiprotozoal new drugs
ReviewAbstract: The 3,5-disubstituted tetrahydro-2H-1,3,5-thiadiazine-2-thione scaffold have found many applicationsPalabras claves:3, 5-thiadiazine-2-thione, Antiprotozoan activity, Tetrahydro-2h-1Autores:Bermello J.C., Fidalgo L.M., Hortensia Rodriguez Cabrera, Navarro M.S., Pineiro R.P.Fuentes:googlescopusSerological Cross-Reaction between Six Thiadiazine by Indirect ELISA Test and Their Antimicrobial Activity
ArticleAbstract: Malaria is a parasitic infection caused by a protozoon of the genus Plasmodium, transmitted to humanPalabras claves:antimicrobial activity, cross-reaction, indirect ELISA, MALARIA, thiadiazineAutores:Abigail Montero-Calderón, Beatriz Pernía, Coro J., Delcy Montoya, Francisco Javier Tingo-Jácome, Hortensia Rodriguez Cabrera, Leslie Espinoza, Lilian M. Spencer, Lilian Maritza Spencer Valero, Lucci E., Mishell OrtizFuentes:googlescopusSynthesis and antiprotozoal evaluation of new N<sup>4</sup>-(benzyl) spermidyl-linked bis(1,3,5-thiadiazinane-2-thiones)
ArticleAbstract: The synthesis and in-vitro antiprotozoal evaluation of novel N 4-(benzyl)spermidyl-linked bis(1,3,5-Palabras claves:1,3,5-thiadiazinane-2-thione, Protozoocidal activity, SpermidineAutores:Coro J., Hortensia Rodriguez Cabrera, Little S., Martín N., Perez-Pineiro R., Súrez M., Yardley V.Fuentes:scopusSynthesis and antiprotozoan evaluation of new alkyl-linked bis(2-thioxo-[1,3,5]thiadiazinan-3-yl) carboxylic acids
ArticleAbstract: Two new series of several alkyl-linked bis(2-thioxo-[1,3,5]thiadiazinan-3- yl) carboxylic acids werePalabras claves:Antiparasitics, chemotherapy, Thiadiazine-2-thioneAutores:Coro J., Gómez-Barrio A., Hortensia Rodriguez Cabrera, Montero D., Nogal-Ruiz J.J., Perez-Pineiro R., Rolón M.S., Suárez Navarro M., Vega C.Fuentes:scopus