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Molecules(3)
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Chemical Conjugation in Drug Delivery Systems
ReviewAbstract: Cancer is one of the diseases with the highest mortality rate. Treatments to mitigate cancer are usuPalabras claves:Biomolecules, Carriers, covalent bioconjugation, Drug delivery systems, linkersAutores:Alberício F., Alexis Eras, Danna Castillo, Hortensia Rodriguez Cabrera, Santiago Nelson Vispo, Suárez Navarro M.Fuentes:scopusChemicals: How good or bad are they?
OtherAbstract:Palabras claves:Autores:Hortensia Rodriguez CabreraFuentes:googlescopusA convenientmicrowave-enhanced solid-phase synthesis of short chain N-methyl-rich peptides
ArticleAbstract: Structural modification of the peptide backbone via N-methylation is a powerful tool to modulate thePalabras claves:Fmoc-N-methyl amino acids, MICROWAVE, Solid-phase peptide synthesisAutores:Alberício F., Hortensia Rodriguez Cabrera, Suárez Navarro M.Fuentes:scopusDevelopment of a novel virtual screening cascade protocol to identify potential trypanothione reductase inhibitors
ArticleAbstract: The implementation of a novel sequential computational approach that can be used effectively for virPalabras claves:Autores:Andrew L.C., Burgos A., Fairlamb A.H., Hortensia Rodriguez Cabrera, Jones D.C., Perez-Pineiro R., Suárez Navarro M., Wishart D.S.Fuentes:googlescopusCell Penetrating Peptides as potential drug carriers
ReviewAbstract: The discovery and development of natural, synthetic or peptidomimetic cell-penetrating peptides (CPPPalabras claves:Blood-brain barrie, Cell penetrating peptides, Molecular transportes, PeptidesAutores:Alberício F., Hortensia Rodriguez Cabrera, Pulido X.C., Royo M.Fuentes:scopusAlkyl-linked bis-THTT derivatives as potent in vitro trypanocidal agents
ArticleAbstract: The effect of several alkyl-linked bis tetrahydro-(2H)-1,3,5-thiadiazine-2- thione (bis-THTT) on LeiPalabras claves:Alkyl-linked bis-THTT anti-protozoal activityAutores:Alvarez A., Atherton R., Coro J., Hortensia Rodriguez Cabrera, Little S., Perez-Pineiro R., Suárez Navarro M., Wharton H., Yardley V.Fuentes:googlescopusAn Androsterone-H<inf>2</inf>@C<inf>60</inf> hybrid: Synthesis, Properties and Molecular Docking Simulations with SARS-Cov-2
ArticleAbstract: We report the synthesis and characterization of a fullerene-steroid hybrid that contains H2@C60 andPalabras claves:cyclopropanation, Fullerenes, Molecular docking, SARS-COV-2, Steroid hybridsAutores:Alberício F., Almagro L., Herranz M.Á., Hortensia Rodriguez Cabrera, Lemos R., Makowski K., Maroto E., Martín N., Molero D., Murata Y., Ortiz O., Suárez Navarro M.Fuentes:scopusFrom Ugi Multicomponent Reaction to Linkers for Bioconjugation
ArticleAbstract: Bioconjugation is a key approach for the development of novel molecular entities with clinical appliPalabras claves:Autores:Alberício F., Cuevas C., Domínguez J.M., Hortensia Rodriguez Cabrera, Pérez-Chacon G., Ramos-Tomillero I., Sánchez‐Madrid F., Somovilla-Crespo B., Zapata J.M.Fuentes:googlescopusEco-friendly methodology to prepare N-heterocycles related to dihydropyridines: Microwave-assisted synthesis of alkyl 4-arylsubstituted-6- chloro-5-formyl-2-methyl-1,4-dihydropyridine-3-carboxylate and 4-arylsubstituted-4,7-dihydrofuro[3,4-b]pyridine-2,5(1H,3H)-dione
ArticleAbstract: Here we describe the efficient synthesis of alkyl 4-arylsubstituted-6- chloro-5- formyl-2-methyl-1,4Palabras claves:Dihydropyridines, Green Chemistry, MICROWAVEAutores:Alberício F., Hortensia Rodriguez Cabrera, Martín N., Martín O., Suárez Navarro M.Fuentes:googlescopusEffect of thiadiazine derivatives on intracellular amastigotes of Leishmania amazonensis
ArticleAbstract: Current therapy for leishmaniasis is not satisfactory. We describe the in vitro antiproliferative efPalabras claves:AMASTIGOTES, LEISHMANIA, thiadiazineAutores:Álvarez A.M.M., Fidalgo L.M., Géigel L.F., Hortensia Rodriguez Cabrera, Navarro M.S., Pineiro R.P.Fuentes:googlescopus