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A Novel Network Science and Similarity-Searching-Based Approach for Discovering Potential Tumor-Homing Peptides from Antimicrobials
ArticleAbstract: Peptide-based drugs are promising anticancer candidates due to their biocompatibility and low toxiciPalabras claves:Cáncer, centrality measure, chemical space network, Complex network, group fusion, in silico drug discovery, motif discovery, Similarity searching, starPep toolbox software, tumor-homing peptideAutores:Agüero-Chapin G., Aguilera-Mendoza L., Antunes A., Hortensia Rodriguez Cabrera, Martinez-Rios F.O., Maylin Romero, Yovani Marrero-PonceFuentes:googlescopusChemical Conjugation in Drug Delivery Systems
ReviewAbstract: Cancer is one of the diseases with the highest mortality rate. Treatments to mitigate cancer are usuPalabras claves:Biomolecules, Carriers, covalent bioconjugation, Drug delivery systems, linkersAutores:Alberício F., Alexis Eras, Danna Castillo, Hortensia Rodriguez Cabrera, Santiago Nelson Vispo, Suárez Navarro M.Fuentes:scopusBioconjugation through Mesitylene Thiol Alkylation
ArticleAbstract: The design and generation of complex multifunctional macromolecular structures by bioconjugation isPalabras claves:Autores:Alberício F., Cuevas C., Domínguez J.M., Hortensia Rodriguez Cabrera, Pérez-Chacon G., Ramos-Tomillero I., Sánchez‐Madrid F., Somovilla-Crespo B., Zapata J.M.Fuentes:googlescopusAlkyl-linked bis-THTT derivatives as potent in vitro trypanocidal agents
ArticleAbstract: The effect of several alkyl-linked bis tetrahydro-(2H)-1,3,5-thiadiazine-2- thione (bis-THTT) on LeiPalabras claves:Alkyl-linked bis-THTT anti-protozoal activityAutores:Alvarez A., Atherton R., Coro J., Hortensia Rodriguez Cabrera, Little S., Perez-Pineiro R., Suárez Navarro M., Wharton H., Yardley V.Fuentes:googlescopusDevelopment of a novel virtual screening cascade protocol to identify potential trypanothione reductase inhibitors
ArticleAbstract: The implementation of a novel sequential computational approach that can be used effectively for virPalabras claves:Autores:Andrew L.C., Burgos A., Fairlamb A.H., Hortensia Rodriguez Cabrera, Jones D.C., Perez-Pineiro R., Suárez Navarro M., Wishart D.S.Fuentes:googlescopusEffect of thiadiazine derivatives on intracellular amastigotes of Leishmania amazonensis
ArticleAbstract: Current therapy for leishmaniasis is not satisfactory. We describe the in vitro antiproliferative efPalabras claves:AMASTIGOTES, LEISHMANIA, thiadiazineAutores:Álvarez A.M.M., Fidalgo L.M., Géigel L.F., Hortensia Rodriguez Cabrera, Navarro M.S., Pineiro R.P.Fuentes:googlescopusEffects of thiadiazine derivatives on the infective capacity of Leishamia amazonensis promastigotes
ArticleAbstract: The infective capacity of Leishmania amazonensis promastigotes was evaluated after they were treatedPalabras claves:AMASTIGOTES, Infective capacity, LEISHMANIA, Promastigotes, thiadiazineAutores:Géigel L.F., Hidalgo L.M., Hortensia Rodriguez Cabrera, Montalvo Álvarez A.M., Navarro M.S., Pineiro R.P.Fuentes:scopusIn vitro activities of thiadiazine derivatives against Leishmania amazonensis
ArticleAbstract: Ten thiadiazine derivatives were tested in vitro for antiparasitic effects against both extracellulaPalabras claves:Antiparasitic drugs, Leishmania amazonensis, amastigotes, promastigotes, Thiadiazine derivatives, antileishmanial activity in vitro, toxicityAutores:Fonseca L., Hortensia Rodriguez Cabrera, Montalvo Álvarez A.M., Monzote L., Perez-Pineiro R., Suárez Navarro M.Fuentes:googlescopusIn vitro and in vivo assays of 3,5-disubstituted-tetrahydro-2H-1,3,5-thiadiazin-2-thione derivatives against Trypanosoma cruzi
ArticleAbstract: Cytotoxicity assays of 24 new 3,5-disubstituted-tetrahydro-2H-1,3,5-thiadiazin-2-thione derivativesPalabras claves:AMASTIGOTES, Antichagasic drugs, Antitrypanosomal activity assays, Cytotoxicity assays, J774 macrophages, Thiadiazine thione derivativesAutores:García-Trevijano J.A.E., Gómez-Barrio A., Hortensia Rodriguez Cabrera, Muelas S., Ochoa C., Perez-Pineiro R., Suárez Navarro M.Fuentes:googlescopusEmpowerment of women in science: Myth or reality
OtherAbstract:Palabras claves:Autores:Hortensia Rodriguez CabreraFuentes:googlescopus