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Co-delivery of hydrophobic and hydrophilic drugsfrom nanoparticle-aptamer bioconjugates
ArticleAbstract: (Figure Presented) Herein we report a novel targeted drug delivery system consisting of nanoparticlePalabras claves:Antitumor agents, conjugation, Dual drug delivery, Nanoparticles, Targeted therapyAutores:Bagalkot V., Basto P.A., Farokhzad O.C., Frank Alexis, Gu F.X., Jon S., Langer R.S., Radovic-Moreno A.F., Zhang L.Fuentes:scopusBright X-ray and up-conversion nanophosphors annealed using encapsulated sintering agents for bioimaging applications
ArticleAbstract: Nanophosphors are promising contrast agents for deep tissue optical imaging applications because thePalabras claves:Autores:Anker J.N., Chen H., Frank Alexis, Hwu S., Mefford O.T., Moore T.L., Qi B., Sulejmanovic D., Wang F.Fuentes:scopusAccelerated iron oxide nanoparticle degradation mediated by polyester encapsulation within cellular spheroids
ArticleAbstract: Nanomaterials including gold nanoparticles, polymeric nanoparticles, and magnetic iron oxide nanoparPalabras claves:Degradation, Iron oxide nanoparticles, Magnetic nanoparticles, spheroidsAutores:Casco M., Frank Alexis, Mattix B.M., Moore T.L., Olsen T.R., Simionescu D.T., Visconti R.P.Fuentes:scopusGraphene quantum dots decorated with imatinib for leukemia treatment
ArticleAbstract: The use of graphene quantum dots as biomedical device and drug delivery system has been increasing.Palabras claves:Biomedical device, drug delivery, Graphene quantum dot, Nanoparticle, Smart materialAutores:Aguiar L., Duarte de Menezes F., Felix D.M., Frank Alexis, Gemini-Piperni S., Junior S.A., Liu Y., Midlej V.d.V.P., Rebelo Alencar L.M., Ricci-Junior E., Santos-Oliveira R., Zhang J., Zhu L.Fuentes:scopusHER-2-targeted nanoparticle-affibody bioconjugates for cancer therapy
ArticleAbstract: (Figure Presented) Affibodies are a class of polypeptide ligand that are potential candidates for tiPalabras claves:Affibodies, Antitumor agents, Nanoparticles, PLA-PEG copolymers, Targeted therapyAutores:Basto P.A., Farokhzad O.C., Frank Alexis, Levy-Nissenbaum E., Marein S.L., Molnar L.K., Pridgen E.M., Radovic-Moreno A.F., Wang A.Z., Westerhof K., Zhang L.Fuentes:scopusIn situ preparation of gold-polyester nanoparticles for biomedical imaging
ArticleAbstract: The synthesis and application of gold nanoparticles (AuNPs) have attracted much attention due to thePalabras claves:Autores:Akasov R., Anker J.N., Attia M.F., Frank Alexis, Ranasinghe M., Whitehead D.C.Fuentes:scopusIron-loaded magnetic nanocapsules for pH-triggered drug release and MRI imaging
ArticleAbstract: Magnetic nanocapsules were synthesized for controlled drug release, magnetically assisted delivery,Palabras claves:Autores:Anker J.N., Chen H., Colvin D.C., Frank Alexis, Gore J.C., Hwu S., Mefford O.T., Moore T.L., Qi B., Sulejmanovic D.Fuentes:scopusSynthesis of brightly PEGylated luminescent magnetic upconversion nanophosphors for deep tissue and dual MRI imaging
ArticleAbstract: A method is developed to fabricate monodispersed biocompatible Yb/Er or Yb/Tm doped β-NaGdF4 upconvePalabras claves:capture and release, deep tissue imaging, Magnetic nanoparticles, MRI, upconversion nanophosphorsAutores:Anker J.N., Chen H., Colvin D.C., Crawford T., Frank Alexis, Gore J.C., Mefford O.T., Moore T.L., Qi B.Fuentes:scopusTarget-Specific Capture of Environmentally Relevant Gaseous Aldehydes and Carboxylic Acids with Functional Nanoparticles
ArticleAbstract: Aldehyde and carboxylic acid volatile organic compounds (VOCs) present significant environmental conPalabras claves:gaseous pollutants, Nanoparticles, poly(ethyleneimine), poly(lactic acid), polymersAutores:Campbell M.L., Dhulekar J., Frank Alexis, Guerra F.D., Whitehead D.C.Fuentes:scopusTargeted aptamer-nanoparticles to diminish drug resistance of cancer cells in vitro study
Conference ObjectAbstract: Using prostate cancer as a model, we report the drug release of Docetaxel and doxorubicin from aptamPalabras claves:aptamer, doxorubicin, Poly (D,L-lactic-co-glycolic acid) (PLGA), Prostate cancer, Targeted deliveryAutores:Basto P.A., Farokhzad O.C., Frank Alexis, Langer R.S., Zhang L.Fuentes:scopus