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scopus(33)
Co-delivery of hydrophobic and hydrophilic drugsfrom nanoparticle-aptamer bioconjugates
ArticleAbstract: (Figure Presented) Herein we report a novel targeted drug delivery system consisting of nanoparticlePalabras claves:Antitumor agents, conjugation, Dual drug delivery, Nanoparticles, Targeted therapyAutores:Bagalkot V., Basto P.A., Farokhzad O.C., Frank Alexis, Gu F.X., Jon S., Langer R.S., Radovic-Moreno A.F., Zhang L.Fuentes:scopusBiomedical applications of hydroxyapatite nanoparticles
ArticleAbstract: Nanotechnologies have the potential to improve current disease diagnosis due to their ability to cirPalabras claves:Bio-imaging, Calcium-phosphate, drug delivery, Gene-delivery, Inorganic nanoparticles, Particulate systemsAutores:Banik B., Frank Alexis, Loo S., Moore T.L.Fuentes:scopusCovalent attachment of low molecular weight poly(ethylene imine) improves tat peptide mediated gene delivery
ArticleAbstract: Covalent attachment of low-molecular weight, branched poly(ethylene imines) (PEIs) is able to improvPalabras claves:Autores:Frank Alexis, Lo S., Wang S.Fuentes:scopusAdjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release
ArticleAbstract: Augmentation of immunogenicity can be achieved by particulate delivery of an antigen and by its co-aPalabras claves:adjuvant, CpG, R848, Resiquimod, Synthetic nanoparticle vaccine, TLR agonistAutores:Altreuter D.H., Basto P.A., Browning E.A., Farokhzad O.C., Frank Alexis, Iannacone M., Ilyinskii P.O., Johnston L.P.M., Kishimoto T.K., Langer R.S., O'Neil C.P., Pittet L.A., Radovic-Moreno A.F., Roy C.J., Shi J., Tonti E., von Andrian U.H.Fuentes:scopusDual Encapsulated Dacarbazine and Zinc Phthalocyanine Polymeric Nanoparticle for Photodynamic Therapy of Melanoma
ArticleAbstract: Purpose: Melanoma is an invasive and very aggressive skin cancer due to its multi-drug resistance thPalabras claves:dacarbazine, Drug resistance, melanoma, Nanoparticle, Photodynamic TherapyAutores:da Silva de Barros A.O., de Oliveira Siqueira L.B., do Reis S.R.R., Frank Alexis, Helal-Neto E., Pinto S.R., Portilho F.L., Rebelo Alencar L.M., Ricci-Junior E., Santos-Oliveira R., Si Amar DahoumaneFuentes:scopusFunctionalized nanoparticles containing MKP-1 agonists reduce periodontal bone loss
ArticleAbstract: Background: Progress over of the past several years has elucidated a role for mitogen-activated protPalabras claves:alveolar bone, auranofin, inflammation, Nanoparticles, periodonticsAutores:Frank Alexis, Kirkwood K.L., Valerio M.S.Fuentes:scopusHER-2-targeted nanoparticle-affibody bioconjugates for cancer therapy
ArticleAbstract: (Figure Presented) Affibodies are a class of polypeptide ligand that are potential candidates for tiPalabras claves:Affibodies, Antitumor agents, Nanoparticles, PLA-PEG copolymers, Targeted therapyAutores:Basto P.A., Farokhzad O.C., Frank Alexis, Levy-Nissenbaum E., Marein S.L., Molnar L.K., Pridgen E.M., Radovic-Moreno A.F., Wang A.Z., Westerhof K., Zhang L.Fuentes:scopusEngineering of targeted nanoparticles for cancer therapy using internalizing aptamers isolated by cell-uptake selection
ArticleAbstract: Figure Persented: One of the major challenges in the development of targeted nanoparticles (NPs) forPalabras claves:aptamer, in vitro selection, Internalization, Nanoparticles, targeted cancer therapyAutores:Chan J.M., Cheng J., Digga E., Farokhzad O.C., Frank Alexis, Langer R.S., Levy-Nissenbaum E., Lupták A., Shi J., Teply B.A., Xiao Z.Fuentes:scopusIntelligent drug-delivery devices based on micro-and nano-technologies
ReviewAbstract: This review focuses on the current drug-delivery modalities in R&D, as well as commercially availablPalabras claves:Autores:Burrow T.J., Chi A.H., Clayton K., D'Hers S., Elman N.M., Frank Alexis, Lewis R., Luciano D.Fuentes:scopusJanus magnetic cellular spheroids for vascular tissue engineering
ArticleAbstract: Cell aggregates, or spheroids, have been used as building blocks to fabricate scaffold-free tissuesPalabras claves:Iron oxide, Magnetic nanoparticles, spheroids, Tissue engineering, Tissue fusionAutores:Casco M., Frank Alexis, Mattix B.M., Olsen T.R., Poole J.T., Reese L., Simionescu A., Simionescu D.T., Visconti R.P., Zhang J.Fuentes:scopus