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Barbiturate- And Thiobarbituarte-Based s-Triazine Hydrazone Derivatives with Promising Antiproliferative Activities
ArticleAbstract: A new class of compounds, which include s-triazine with pyrimidinetrione or thiopyrimidinedione moiePalabras claves:Autores:Al-Rasheed H.H., Alberício F., B. G. De la Torre, Dahlous K.A., El-Faham A., Sharma A., Sholkamy E.N.Fuentes:scopus1,3,5-Triazino Peptide Derivatives: Synthesis, Characterization, and Preliminary Antileishmanial Activity
ArticleAbstract: A library of short di-, tri-, and tetra-peptides with an s-triazine moiety at the N terminus and eitPalabras claves:1,3,5-triazine derivatives, antileishmanial compounds, morpholines, Peptides, piperidinesAutores:Abd El-Rahman M.M., Alberício F., B. G. De la Torre, Bekhit A.A., El-Faham A., Khalil H.H., Khattab S.N.Fuentes:scopus2022 FDA TIDES (Peptides and Oligonucleotides) Harvest
ArticleAbstract: A total of 37 new drug entities were approved in 2022; although that year registered the lowest numbPalabras claves:drugs, FDA, gadopiclenol, lutetium ( Lu) vipivotide tetraxetan 177, Oligonucleotides, Peptides, terlipressin, tirzepatide, vutrisiranAutores:Al Musaimi O., Al Shaer D.M., Alberício F., B. G. De la TorreFuentes:scopusA BODIPY-embedding miltefosine analog linked to cell-penetrating Tat(48-60) peptide favors intracellular delivery and visualization of the antiparasitic drug
ArticleAbstract: Therapeutic application of many drugs is often hampered by poor or denied access to intracellular taPalabras claves:BODIPY, cell-penetrating peptide, Dual fluorescent labeling, Miltefosine, Monitoring of intracellular drug delivery, Reversion of resistanceAutores:Abengózar M.Á., Amat-Guerri F., Andreu D., B. G. De la Torre, Hornillos V., Luque-Ortega J.R., Rivas L., Ulises Acuña A.Fuentes:scopusCorrigendum: Pyrazolyl-s-triazine with indole motif as a novel of epidermal growth factor receptor/cyclin-dependent kinase 2 dual inhibitors(Front. Chem., (2022), 10, (1078163), 10.3389/fchem.2022.1078163)
OtherAbstract: In the original article, there was an error in the Affiliation for Samha Al Ayoubi2. Instead of “SamPalabras claves:anticancer profile, apoptosis, EGFR/CDK-2, ÍNDOLE, pyrazolyl-s-triazineAutores:Al Ayoubi S., Al Zoubi M., Al-Rasheed H.H., Alberício F., Aldalbahi A., Ali M., Alshaer W., B. G. De la Torre, Barakat A., El-Faham A., Nafie M.S., Shawish I.Fuentes:scopusAcetic Acid Mediated for One-Pot Synthesis of Novel Pyrazolyl s-Triazine Derivatives for the Targeted Therapy of Triple-Negative Breast Tumor Cells (MDA-MB-231) via EGFR/PI3K/AKT/mTOR Signaling Cascades
ArticleAbstract: Here, we described the synthesis of novel pyrazole-s-triazine derivatives via an easy one-pot procedPalabras claves:anticancer profile, apoptosis, DMF-DMA, EGFR/PI3K/AKT/mTOR, One-pot synthesis, pyrazolyl-s-triazineAutores:Al Zoubi M., Alberício F., Aldalbahi A., Alqudah D.A., Alshaer W., B. G. De la Torre, Barakat A., Daoud F., El-Faham A., Hatmal M.M., Haukka M., Nafie M.S., Sharma A., Shawish I.Fuentes:scopusExploiting the Thiobarbituric Acid Scaffold for Antibacterial Activity
ArticleAbstract: Thiobarbituric acid (TBA) has been considered a privileged structure for developing antimicrobial agPalabras claves:Antibiotics, barbituric acid, nanoformulations, Thiobarbituric acidAutores:Alberício F., Almarhoon Z.M., B. G. De la Torre, El-Faham A., Hazzah H.A., Noki S., Sharma A., Zamisa S.J.Fuentes:scopusEnamine barbiturates and thiobarbiturates as a new class of bacterial urease inhibitors
ArticleAbstract: Urease is a therapeutic target associated with several important diseases and health problems. BasedPalabras claves:Barbituric, DFT, Pyrimidine-trione, Thiobarbituric, Urease inhibitorsAutores:Al-Majid A.M., Alberício F., Ali M., Ashraf S., B. G. De la Torre, Barakat A., Choudhary M.I., El-Faham A., Ul-Haq Z., Yousuf S.Fuentes:scopusNovel 4,6-disubstituted s-triazin-2-yl amino acid derivatives as promising antifungal agents
ArticleAbstract: A novel series of 4,6-disubstituted s-triazin-2-yl amino acid derivatives was prepared and characterPalabras claves:2,4,6-trichlorotriazine, Antifungal, Candida Albicans, N-myristoltransferase, TCT, Triazine amino acidAutores:Alberício F., Alhameed R.A., Almarhoon Z.M., B. G. De la Torre, El-Faham A., Khan S.A., Sharma A., Sholkamy E.N., Ul-Haq Z.Fuentes:scopusInsights into the chemistry of the amphibactin–metal (M<sup>3+</sup>) interaction and its role in antibiotic resistance
ArticleAbstract: We have studied the diversity and specificity of interactions of amphibactin produced by Vibrio genuPalabras claves:Autores:Alberício F., B. G. De la Torre, Kaipanchery V., Sharma A.Fuentes:scopus