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Farmacología y terapéutica(5)
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scopus(7)
An optimized Fmoc synthesis of human defensin 5
Conference ObjectAbstract: Human α-defensin 5 (DEF5), expressed by the Paneth cells of human small intestine, plays an importanPalabras claves:ChemMatrix resin, Fmoc solid-phase peptide synthesis, Human defensin 5, Pseudoproline dipeptidesAutores:Andreu D., B. G. De la Torre, Valle J., Vernieri E.Fuentes:scopus2-Methyltetrahydrofuran and cyclopentyl methyl ether for green solid-phase peptide synthesis
ArticleAbstract: 2-MeTHF and CPME were evaluated as greener alternatives for the most employed solvents in peptide syPalabras claves:2-methyltetrahydrofuran, Cyclopentyl methyl ether, Green solvents, Peptide synthesis, Solid-phase peptide synthesisAutores:Acosta G.A., Alberício F., B. G. De la Torre, El-Faham A., Govender T., Jad Y.E., Khattab S.N., Kruger H.G.Fuentes:scopusA BODIPY-embedding miltefosine analog linked to cell-penetrating Tat(48-60) peptide favors intracellular delivery and visualization of the antiparasitic drug
ArticleAbstract: Therapeutic application of many drugs is often hampered by poor or denied access to intracellular taPalabras claves:BODIPY, cell-penetrating peptide, Dual fluorescent labeling, Miltefosine, Monitoring of intracellular drug delivery, Reversion of resistanceAutores:Abengózar M.Á., Amat-Guerri F., Andreu D., B. G. De la Torre, Hornillos V., Luque-Ortega J.R., Rivas L., Ulises Acuña A.Fuentes:scopusNovel formulation of antimicrobial peptides enhances antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA)
ArticleAbstract: Antimicrobial peptides (AMPs) have the ability to penetrate as well as transport cargo across bacterPalabras claves:Amps, Liposomes, MRSA, Peptide-lipidation, pH responseAutores:Agrawal N., Alberício F., B. G. De la Torre, Faya M., Govender T., Hazzah H.A., Maji R., Mocktar C., Nkambule B., Omolo C.A., Rambharose S., Walvekar P.Fuentes:scopusMicroreactors for peptide synthesis: Looking through the eyes of twenty first century!!!
OtherAbstract: The twenty first century has witnessed several advances in synthetic chemistry, among them microreacPalabras claves:Amide formation, Applications, Continuous flow, Microreactors, Peptide synthesisAutores:Alberício F., B. G. De la Torre, Cherkupally P., Govender T., Kruger H.G., Ramesh S.Fuentes:scopusVipericidins: A novel family of cathelicidin-related peptides from the venom gland of South American pit vipers
ArticleAbstract: Cathelicidins are phylogenetically ancient, pleiotropic host defense peptides-also called antimicrobPalabras claves:Antimicrobial peptides, Peptide synthesis, Reptilian CRAMPs, Therapeutic peptide, Venom peptides, VipericidinsAutores:Andreu D., B. G. De la Torre, Barron A., Falcao C., Pérez-Peinado C., Rádis-Baptista G.Fuentes:scopusSolid-phase peptide synthesis (SPPS), C-terminal vs. side-chain anchoring: A reality or a myth
OtherAbstract: Here we review the strategies for the solid-phase synthesis of peptides starting from the side chainPalabras claves:C-terminal acid peptide, Side-chain anchoring, Solid-phase peptide synthesis, Stepwise elongationAutores:Acosta G.A., Alberício F., B. G. De la Torre, Cherkupally P., Govender T., Kruger H.G., Ramesh S.Fuentes:scopus