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Peptide therapeutics 2.0
OtherAbstract:Palabras claves:Autores:Alberício F., B. G. De la TorreFuentes:scopusInvestigation of the N-terminus amino function of Arg<inf>10</inf>-Teixobactin
ArticleAbstract: Teixobactin is a recently described antimicrobial peptide that shows high activity against gram-posiPalabras claves:Antimicrobial peptides, Cyclic depsipeptides, Lipophilicity, Solid-phase peptide synthesis, TeixobactinAutores:Alberício F., B. G. De la Torre, El-Faham A., Monaim S.A.H.A., Noki S., Ramchuran E.J.Fuentes:scopusScope and limitations of γ-valerolactone (GVL) as a green solvent to be used with base for FMOC removal in solid phase peptide synthesis
ArticleAbstract: GVL is a green solvent used in Fmoc-based solid-phase peptide synthesis. It is susceptible to ring oPalabras claves:4-methylpiperidine, Acyl piperidide, DFT, IR, NMR, PiperidineAutores:Alberício F., B. G. De la Torre, Kumar A., Sharma A.Fuentes:scopusS-triazine: A privileged structure for drug discovery and bioconjugation
ArticleAbstract: This review provides an overview of the broad applicability of s-triazine. Our many years working wiPalabras claves:azide, Nucleophiles, Orthogonal chemoselectivity, S-triazineAutores:Alberício F., B. G. De la Torre, El-Faham A., Sharma A., Sheyi R.Fuentes:scopusSynthesis and antimicrobial activity of a new series of thiazolidine-2,4-diones carboxamide and amino acid derivatives
ArticleAbstract: Novel thiazolidine-2,4-dione carboxamide and amino acid derivatives were synthesized in excellent yiPalabras claves:Antibacterial activity, OxymaPure, Thiazolidine-2,4-dione amino acid ester, Thiazolidine-2,4-dione carboxamideAutores:Alberício F., Alhameed R.A., Almarhoon Z.M., B. G. De la Torre, Bukhari S.I., El-Faham A.Fuentes:scopusTOMBU and COMBU as novel uronium-type peptide coupling reagents derived from oxyma-b
ArticleAbstract: Here we describe two novel uronium salts, TOMBU and COMBU, derived from the recently described OxymaPalabras claves:amino acids, Coupling reagents, Oxyma-B, Peptide synthesis, Solid-phase peptide synthesisAutores:Alberício F., B. G. De la Torre, El-Faham A., Govender T., Jad Y.E., Khattab S.N., Kruger H.G.Fuentes:scopusThe Pharmaceutical Industry in 2022: An Analysis of FDA Drug Approvals from the Perspective of Molecules
ReviewAbstract: While 2021 ended with the world engulfed in the COVID-19 Omicron wave, 2022 has ended in almost allPalabras claves:Antibodies, biologics, chemical entities, fluorine-based drugs, imaging, Natural products, new chemical entities, Oligonucleotides, Peptides, TIDESAutores:Alberício F., B. G. De la TorreFuentes:scopusThe antiproliferative and apoptotic effect of a novel synthesized s-triazine dipeptide series, and toxicity screening in zebrafish embryos
ArticleAbstract: Several derivatives containing morpholine/piperidine, anilines, and dipeptides as pending moieties wPalabras claves:Anti-proliferative activity, apoptosis, Dipeptides, S-triazine, zebrafishAutores:Alberício F., Alhameed R.A., Almarhoon Z.M., B. G. De la Torre, El-Faham A., Farooq M., Malebari A.M., Sharma A., Wadaan M.A.M.Fuentes:scopus