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Acute Vhl gene inactivation induces cardiac HIF-Dependent erythropoietin gene expression
ArticleAbstract: Von Hippel Lindau (Vhl) gene inactivation results in embryonic lethality. The consequences of its inPalabras claves:Autores:Albacete-Albacete L., Aragonés J., Balsa E., Elorza A., Fernández-Criado C., Fuertes E., Manuel Ortiz de Landázuri, Miró-Murillo M., Ordóñez A., Soro-Arnáiz I., Vara-Vega A., Vazquez S.N.Fuentes:scopusMyeloid hypoxia-lnducible factors in inflammatory diseases
ArticleAbstract: Hypoxia inducible factors (HIFI and HIF2) have emerged as central regulators of the activity of myelPalabras claves:Hypoxia, Hypoxia-inducible factor (HIF), inflammation, MacrophagesAutores:Acosta-Lborra B., Aragonés J., Elorza A., Manuel Ortiz de LandázuriFuentes:scopusHIF2α Acts as an mTORC1 Activator through the Amino Acid Carrier SLC7A5
ArticleAbstract: The mammalian target of rapamycin (mTOR) pathway, which is essential for cell proliferation, is reprPalabras claves:Autores:Acosta-Iborra B., Albacete-Albacete L., Aragonés J., de Cárcer G., Elorza A., Giménez-Bachs J.M., Malumbres M., Manuel Ortiz de Landázuri, Marsboom G., Martín del Río R., Meléndez-Rodríguez F., Ordóñez A., Rodríguez-Vaello V., Salinas A., Sánchez-Prieto R., Sánchez‐Madrid F., Serrano-Oviedo L., Soro-Arnáiz I., Vara-Vega A.Fuentes:scopusMacrophage oxygen sensing modulates antigen presentation and phagocytic functions involving IFN-γ production through the HIF-1α transcription factor
ArticleAbstract: Low oxygen tension areas are found in inflamed or diseased tissues where hypoxic cells induce survivPalabras claves:Autores:Acosta-Iborra B., Aragonés J., Calzada M.J., Elorza A., Manuel Ortiz de Landázuri, Martín-Cofreces N.B., Martin-Puig S., Miro M., Olazabal I.M., Sánchez‐Madrid F.Fuentes:scopus