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ODS 3: Salud y bienestar(3)
ODS 10: Reducción de las desigualdades(2)
ODS 9: Industria, innovación e infraestructura(2)
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scopus(3)
METTL1-mediated m<sup>7</sup>G modification of Arg-TCT tRNA drives oncogenic transformation
ArticleAbstract: The emerging “epitranscriptomics” field is providing insights into the biological and pathological rPalabras claves:Arg-TCT, Cáncer, m G 7, METTL1, N -methylguanosine 7, oncogene, translation, tRNAAutores:Ali R., Aspris D., Bernardes G.J.L., Bradley A., De Braekeleer E., Esteban A. Orellana, Fischer E.S., Garyfallos D.A., Gregory R.I., Gu M., Gutierrez A., Lim J., Liu Q., Mikutis S., Pirouz M., Sendinc E., Slack F.J., Tzelepis K., Vassiliou G.S., Yankova E., Zhang W.Fuentes:scopusSynthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias
ArticleAbstract: Resistance to asparaginase, an antileukemic enzyme that depletes asparagine, is a common clinical prPalabras claves:acute leukemia, asparaginase, asparagine, Drug resistance, FBXW7, GSK3, proteasomal degradation, protein ubiquitination, synthetic lethality, Wnt signalingAutores:Bauer D.E., Degar J., Esteban A. Orellana, Gregory R.I., Gutierrez A., Hinze L., Karim S., McGuckin C., Neuberg D.S., Pfirrmann M., Sacher J., Stanulla M., Stegmaier K., Stevenson K.E., Vinjamur D., Wagner F.F.Fuentes:scopustRNA dysregulation and disease
ReviewAbstract: tRNAs are key adaptor molecules that decipher the genetic code during translation of mRNAs in proteiPalabras claves:Autores:Esteban A. Orellana, Gregory R.I., Siegal E.Fuentes:scopus