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tRNA dysregulation and disease
ReviewAbstract: tRNAs are key adaptor molecules that decipher the genetic code during translation of mRNAs in proteiPalabras claves:Autores:Esteban A. Orellana, Gregory R.I., Siegal E.Fuentes:scopusSynthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias
ArticleAbstract: Resistance to asparaginase, an antileukemic enzyme that depletes asparagine, is a common clinical prPalabras claves:acute leukemia, asparaginase, asparagine, Drug resistance, FBXW7, GSK3, proteasomal degradation, protein ubiquitination, synthetic lethality, Wnt signalingAutores:Bauer D.E., Degar J., Esteban A. Orellana, Gregory R.I., Gutierrez A., Hinze L., Karim S., McGuckin C., Neuberg D.S., Pfirrmann M., Sacher J., Stanulla M., Stegmaier K., Stevenson K.E., Vinjamur D., Wagner F.F.Fuentes:scopus