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Characterization of antimicrobial, antioxidant, and leishmanicidal activities of Schiff base derivatives of 4-aminoantipyrine
ArticleAbstract: Our main interest is the characterization of compounds to support the development of alternatives toPalabras claves:antimicrobial activity, Cytotoxicity, LEISHMANIA, Schiff base synthesisAutores:Ana Maria Poveda, Araya-Maturana R., Beske T., Jessica Mora, Jorge Hebkp_redia-Moya, Jorge Pérez-Barrera, Lizeth Dobronski, Olalla Barreiro-Costa, Patricio Rojas-Silva, Rommel Guevara, rommy TeranFuentes:scopusFri-1 is an anti-cancer isoquinolinequinone that inhibits the mitochondrial bioenergetics and blocks metabolic shifts by redox disruption in breast cancer cells
ArticleAbstract: Since breast cancer (BC) cells are dependent on mitochondrial bioenergetics for promoting proliferatPalabras claves:2-oxoglutarate dehydrogenase (OGDH), AMP-activated kinase (AMPK) signaling, CPI-613, Devimistat, Mitocans, Mitochondria, Tricarboxylic acid (TCA) cycleAutores:Araya-Maturana R., Córdova-Delgado M., Fuentes-Retamal S., Guzmán-Rivera D., López-Torres C., Oney O. Ramírez-Rodríguez, Palominos C., Urra F.A.Fuentes:scopusExperimental and theoretical reduction potentials of some biologically active ortho-carbonyl para-quinones
ArticleAbstract: The rational design of quinoneswith specific redox properties is an issue of great interest becausePalabras claves:Cyclic Voltammetry, density functional theory, Quinones, Redox potential, SemiquinoneAutores:Araya-Maturana R., Martínez-Cifuentes M., Oney O. Ramírez-Rodríguez, Salazar R., Weiss-López B.Fuentes:scopusEffects of simple and angular chromones on tumor cell respiration
ArticleAbstract: A set of structurally related compounds incorporating a chromone moiety as an essential component ofPalabras claves:Cáncer, Cell respiration, ChromoneAutores:Araya-Maturana R., Donoso-Tauda O., Ferreira J., Hernández J.T., Jorge Hebkp_redia-Moya, Pavani M., Pessoa-Mahana H., Vera M., Weiss-López B.Fuentes:googlescopusMitochondria: A promising target for anticancer alkaloids
ArticleAbstract: A great number of alkaloids exhibit high potential in cancer research. Some of them are anticancer dPalabras claves:alkaloids, apoptosis, Cancer cells, DELIVERY, Endoplasmic reticulum, Mitochondria, targetingAutores:Araya-Maturana R., Córdova-Delgado M., Ferreira J., Oney O. Ramírez-Rodríguez, Pessoa-Mahana H., Urra F.A., Weiss-López B.Fuentes:scopusSmall structural changes on a hydroquinone scaffold determine the complex I inhibition or uncoupling of tumoral oxidative phosphorylation
ArticleAbstract: Mitochondria participate in several distinctiveness of cancer cell, being a promising target for thePalabras claves:Anti-cancer agents, Complex I, Hydroquinones, Oxidative phosphorylation, UncouplersAutores:Acevedo-Arévalo L., Andrea Orellana Manzano, Araya-Maturana R., Córdova-Delgado M., Ferreira J., González-Vivanco J.M., Lapier M., Martínez-Cifuentes M., Millas-Vargas J.P., Oney O. Ramírez-Rodríguez, Pavani M., Pessoa-Mahana H., Urra F.A., Weiss-López B.Fuentes:scopus