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Chemical Conjugation in Drug Delivery Systems
ReviewAbstract: Cancer is one of the diseases with the highest mortality rate. Treatments to mitigate cancer are usuPalabras claves:Biomolecules, Carriers, covalent bioconjugation, Drug delivery systems, linkersAutores:Alberício F., Alexis Eras, Danna Castillo, Hortensia Rodriguez Cabrera, Santiago Nelson Vispo, Suárez Navarro M.Fuentes:scopus15-Hydroxygermacranolides as Sources of Structural Diversity: Synthesis of Sesquiterpene Lactones by Cyclization and Rearrangement Reactions. Experimental and DFT Study
ArticleAbstract: A study on the electrophile-induced rearrangement of two 15-hydroxygermacranolides, salonitenolide aPalabras claves:Autores:Álvarez-Calero J.M., Enrique Ruiz-Reyes, Jaraíz M., Jorge Z.D., López-Pérez J.L., Massanet G.M., Rubio J.E., Suárez Navarro M.Fuentes:googlescopus3,4-Dihydro-2(1H)-Pyridones as Building Blocks of Synthetic Relevance
ReviewAbstract: 3,4-Dihydro-2(1H)-pyridones (3,4-DHPo) and their derivatives are privileged structures, which has inPalabras claves:1,4-DHPs, 3,4-DHPo, multicomponent reaction, nonconventional synthesis, synthetic precursorsAutores:Alberício F., Castro V., Hortensia Rodriguez Cabrera, Ruth Oropeza, Sisa P. Chalán-Gualán, Suárez Navarro M.Fuentes:googlescopusA convenientmicrowave-enhanced solid-phase synthesis of short chain N-methyl-rich peptides
ArticleAbstract: Structural modification of the peptide backbone via N-methylation is a powerful tool to modulate thePalabras claves:Fmoc-N-methyl amino acids, MICROWAVE, Solid-phase peptide synthesisAutores:Alberício F., Hortensia Rodriguez Cabrera, Suárez Navarro M.Fuentes:scopusA joint theoretical and experimental structural study of 5-carboxyethyl-3-(2′-furfurylmethyl) tetrahydro-2H-1,3,5-thiadiazine-2-thione
ArticleAbstract: X-Ray analysis and semiempirical AM1 and ab initio HF/3-21G* and HF/6-31G* calculations reveal a favPalabras claves:Structural study, Tetrahydro-2H-1,3,5-thiadiazines, Theoretical calculations, X-ray analysisAutores:Blaton N.M., De Ranter C., Hortensia Rodriguez Cabrera, Martín N., Novoa H., Ochoa E., Peeters O.M., Perez-Pineiro R., Seoane C., Suárez Navarro M.Fuentes:googlescopusA study of electrospray mass spectrometry of new 1,4-dihydropyridines endowed with long alkyl chains [1]
OtherAbstract:Palabras claves:Autores:Alvarez A., De Armas M., Kayali N., Martín N., Martínez-Álvarez R., Oney O. Ramírez-Rodríguez, Seoane C., Suárez Navarro M.Fuentes:scopusA study of the electrospray ionisation and ion-trap fragmentation of [M - H]<sup>-</sup> ions of new 3,5-disubstituted tetrahydro-2H-1,3,5-thiadiazin-2-thiones
ArticleAbstract: The electrospray ionisation (ESI) in negative mode of the pharmacologically significant 3,5-disubstiPalabras claves:Autores:Hortensia Rodriguez Cabrera, Kayali N., Martín N., Martínez-Álvarez R., Perez-Pineiro R., Seoane C., Suárez Navarro M.Fuentes:scopusDevelopment of a novel virtual screening cascade protocol to identify potential trypanothione reductase inhibitors
ArticleAbstract: The implementation of a novel sequential computational approach that can be used effectively for virPalabras claves:Autores:Andrew L.C., Burgos A., Fairlamb A.H., Hortensia Rodriguez Cabrera, Jones D.C., Perez-Pineiro R., Suárez Navarro M., Wishart D.S.Fuentes:googlescopusAlkyl-linked bis-THTT derivatives as potent in vitro trypanocidal agents
ArticleAbstract: The effect of several alkyl-linked bis tetrahydro-(2H)-1,3,5-thiadiazine-2- thione (bis-THTT) on LeiPalabras claves:Alkyl-linked bis-THTT anti-protozoal activityAutores:Alvarez A., Atherton R., Coro J., Hortensia Rodriguez Cabrera, Little S., Perez-Pineiro R., Suárez Navarro M., Wharton H., Yardley V.Fuentes:googlescopusAlkylation of some pyrimidine and purine derivatives using microwave-assisted methods
ArticleAbstract: N-Alkylation of adenine (1), guanine (2) and 6-amino-2-thiouracil (3) with different halides has beePalabras claves:Autores:Cabrales N., Hortensia Rodriguez Cabrera, Lam A., Loupy A., Perez-Pineiro R., Suárez Navarro M.Fuentes:googlescopus