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Anti-VSG antibodies induce an increase in Trypanosoma evansi intracellular Ca<sup>2+</sup> concentration
ArticleAbstract: Trypanosoma evansi and Trypanosoma vivax have shown a very high immunological cross-reactivity. AntiPalabras claves:Antibodies, calcium, complement, TRYPANOSOMA EVANSI, Trypanosoma vivax, variant surface glycoproteinsAutores:Benaím G., Bubis J., Carrasquel L.M., Garcia-Marchan Y., Graciela Lucía Uzcanga, Mendoza M., Mijares A., Pacheco R., Rojas H., Serrano-Martín X.Fuentes:googlescopusAmiodarone and miltefosine act synergistically against Leishmania mexicana and can induce parasitological cure in a murine model of cutaneous leishmaniasis
ArticleAbstract: Leishmaniasis is parasitic disease that is an important problem of public health worldwide. IntramusPalabras claves:Autores:Benaím G., M. De Lucca, Martínez J.C., Mendoza-León A., Payares G., Serrano-Martín X.Fuentes:scopusEvidence of the presence of a calmodulin-sensitive plasma membrane Ca<sup>2+</sup>-ATPase in Trypanosoma equiperdum
ArticleAbstract: Trypanosoma equiperdum belongs to the subgenus Trypanozoon, which has a significant socio-economic iPalabras claves:Animal trypanosomiasis, Ca -ATPase 2+, Calmodulin, PMCA, Trypanosoma equiperdumAutores:Benaím G., Cervino V., Graciela Lucía Uzcanga, Mendoza M., Peréz-Gordones M.C., Ramírez-Iglesias J.R.Fuentes:googlescopusEffect of a methylenedioxy-flavonoid isolated from iresine diffusa on the cellular viability of leishmania mexicana and the intracellular homeostasis of Ca<sup>2+</sup>
ArticleAbstract: The hemoflagellate parasite Leishmania is the cause of leishmaniasis, which depending on the infectiPalabras claves:Ca 2+, flavonoids, Leishmania mexicanaAutores:Alírica Isabel Suárez, Benaím G., De Gouveia Y., Hernández-Rodríguez V., Rodríguez-Durán J.Fuentes:scopusDronedarone, an amiodarone analog with improved anti-Leishmania mexicana efficacy
ArticleAbstract: Dronedarone and amiodarone are cationic lipophilic benzofurans used to treat cardiac arrhythmias. ThPalabras claves:Autores:Alírica Isabel Suárez, Benaím G., Casanova P., Concepcion J.L., Hernández-Rodríguez V., Liu Y.L., Mujica-Gonzalez S., Oldfield E., Pániz-Mondolfi A.E., Parra-Gimenez N., Plaza-Rojas L.Fuentes:scopusIn vitro anti-Trypanosoma cruzi activity of dronedarone, a novel amiodarone derivative with an improved safety profile
ArticleAbstract: Amiodarone, a commonly used antiarrhythmic, is also a potent and selective anti-Trypanosoma cruzi agPalabras claves:Autores:Benaím G., Garcia-Marchan Y., Graciela Lucía Uzcanga, Hernández-Rodríguez V., Mujica-Gonzalez S., Pániz-Mondolfi A.E., Parra-Gimenez N., Plaza-Rojas L., Silva M.L.Fuentes:googlescopusIdentification of a sphingosine-sensitive Ca<sup>2+</sup> channel in the plasma membrane of Leishmania mexicana
ArticleAbstract: The disruption of the intracellular Ca2+ homeostasis of Leishmania mexicana represents a major targePalabras claves:Calcium channel, LEISHMANIA, Sphingosine Ca 2+, trypanosomatidsAutores:Benaím G., Figarella K., Garcia-Marchan Y., Graciela Lucía Uzcanga, Reyes C.Fuentes:googlescopusVenezuela's humanitarian crisis, resurgence of vector-borne diseases, and implications for spillover in the region
ReviewAbstract: In the past 5–10 years, Venezuela has faced a severe economic crisis, precipitated by political instPalabras claves:Autores:Acosta-Serrano A., Acquattela H., Basanez M.G., Benaím G., Blohm G., Carrasco H.J., Colmenares L.A., Conn J.E., Crainey J.L., de Noya B.A., Espinoza R., Ferguson H.M., Freilij H., Graterol-Gil M.C., Grillet M.E., Haydon D.T., Hernandez-Castro L.E., Hernandez-Pereira C.E., Hernández-Villena J.V., Hotez P.J., Jaime Alfredo Costales, Juan Carlos Navarro, Kato H., Lamberton P.H.L., Lednicky J.A., Llewellyn M.S., Luz S.L.B., Mario J. Grijalva, Marquez M., Martinez C.E., Mas-Coma S., Miles M.A., Mogollon-Mendoza A.C., Moreno J.D., Morris J.G., Noya O., Pániz-Mondolfi A.E., Plaza-Morr J.D., Ramírez J.D., Ramirez J.L., Rodriguez M., Schwabl P., Segovia M.J., Streicker D.G., Tami A., Urbina J.A., Villegas L., Vincenti-Gonzalez M.F.Fuentes:scopusStructural Analysis and Diversity of Calmodulin-Binding Domains in Membrane and Intracellular Ca<sup>2+</sup>-ATPases
ArticleAbstract: The plasma membrane and autoinhibited Ca2+-ATPases contribute to the Ca2+ homeostasis in a wide variPalabras claves:Autoinhibited Ca -ATPases 2+, Ca -ATPases 2+, Calcium signaling, Calmodulin, Calmodulin-binding domain, PMCAAutores:Benaím G., Cisneros-Montufar S., Juan Carlos Navarro, Mantilla G., Mendoza M., Peréz-Gordones M.C., Ramírez-Iglesias J.R.Fuentes:scopusThe marine sponge toxin agelasine B increases the intracellular Ca <sup>2+</sup> concentration and induces apoptosis in human breast cancer cells (MCF-7)
ArticleAbstract: Purpose: In search for new drugs derived from natural products for the possible treatment of cancer,Palabras claves:Agelasine B, calcium, Natural products, SERCA, ThapsigarginAutores:Alírica Isabel Suárez, Arvelo F.A., Benaím G., Chirino P., Colman L., Compagnone R.S., de Sanctis J.B., Dipolo R., Felibertt P., Galindo-Castro I., Mayora A., Pimentel A.A., Rojas H., Silva M.L., Sojo F.J.Fuentes:scopus