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Nuclear DNA replication and repair in parasites of the genus Leishmania: Exploiting differences to develop innovative therapeutic approaches
ReviewAbstract: Leishmaniasis is a common tropical disease that affects mainly poor people in underdeveloped and devPalabras claves:DNA damage, DNA replication, drugs, genome stability, LEISHMANIAAutores:Ana Maria Poveda, Beaty D., Beske T., Eliana Lara-Barba, Graciela Lucía Uzcanga, Juan Carlos Navarro, María Fernanda Gutiérrez-Bravo, Pasero P., rommy Teran, Washington Benítez-OrtízFuentes:googlescopusMec1 Is Activated at the Onset of Normal S Phase by Low-dNTP Pools Impeding DNA Replication
ArticleAbstract: The Mec1 and Rad53 kinases play a central role during acute replication stress in budding yeast. ThePalabras claves:ATR, budding yeast, cell cycle, DNA replication, dNTP synthesis, fork collapse, Mec1, mitotic catastrophe, replication timing, S phase checkpointAutores:Ana Maria Poveda, Barthe A., Chabes A., Forey R., Ginalski K., Lambert R., Lengronne A., Padioleau I., Pardo B., Pasero P., Renard C., Sharma S., Skrzypczak M.Fuentes:googlescopusTranscription and replication: Breaking the rules of the road causes genomic instability
ArticleAbstract: Replication and transcription machineries progress at high speed on the same DNA template, which inePalabras claves:DNA replication, Genomic instability, R-loops, Transcription-associated recombinationAutores:Ana Maria Poveda, le Clech M., Pasero P.Fuentes:googlescopus