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Bioorganic and Medicinal Chemistry(1)
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scopus(5)
QSAR analysis on tacrine-related acetylcholinesterase inhibitors
ArticleAbstract: Background: The evaluation of the clinical effects of Tacrine has shown efficacy in delaying the detPalabras claves:Acetylcholinesterase Inhibitor, Alzheimer's disease, QSAR Theory, Tacrine, ValidationAutores:Honarparvar B., Mercader A.G., Pablo R. Duchowicz, Romanelli G.P., Saavedra L.M., Wong K.Y.Fuentes:scopusQSAR applications during last decade on inhibitors of acetylcholinesterase in Alzheimer's disease
ArticleAbstract: This article reviews multi-criteria QSAR applications on Acetylcholinesterase inhibitors as palliatiPalabras claves:Acetylcholinesterase, Alzheimer's disease, CoMFA, CoMSIA, Medicinal chemistry, Molecular descriptors, QSAR TheoryAutores:Castro E.A., Mercader A.G., Pablo R. Duchowicz, Wong K.Y.Fuentes:scopusQSAR pbkp_rediction of inhibition of aldose reductase for flavonoids
ArticleAbstract: We performed a pbkp_redictive analysis based on quantitative structure-activity relationships (QSAR)Palabras claves:Aldose reductase inhibition, Cataract prevention, Dragon molecular descriptors, Enhanced replacement method, Flavone derivative, Genetic Algorithm, QSAR, Replacement methodAutores:Autino J.C., Bennardi D.O., Castro E.A., Fernandez F.M., Mercader A.G., Pablo R. Duchowicz, Romanelli G.P.Fuentes:scopusQSAR study of the DPPH radical scavenging activity of di(hetero)arylamines derivatives of benzo[b]thiophenes, halophenols and caffeic acid analogues
ArticleAbstract: We performed a pbkp_redictive analysis based on Quantitative Structure-Activity Relationships (QSAR)Palabras claves:Benzo[b]thiophenes, Caffeic acid analogues, Di(hetero)arylamines, Halophenols, QSAR, Radical scavenging activityAutores:Castro E.A., Lee A., Mercader A.G., Pablo R. Duchowicz, Pomilio A.B.Fuentes:scopusPbkp_redictive QSPR study of the dissociation constants of diverse pharmaceutical compounds
ArticleAbstract: The objective of the article was to perform a pbkp_redictive analysis, based on quantitative structuPalabras claves:Enhanced replacement method, Pharmaceutical compounds, pK a, QSPRAutores:Castro E.A., Fernandez F.M., Goodarzi M., Mercader A.G., Pablo R. DuchowiczFuentes:scopus