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Comparative Neuroregenerative Effects of C-Phycocyanin and IFN-Beta in a Model of Multiple Sclerosis in Mice
ArticleAbstract: Multiple Sclerosis (MS) therapies approved so far are unable to effectively reverse the chronic phasPalabras claves:C-Phycocyanin, EAE, IFN-beta, Multiple Sclerosis, Neuroregeneration, RemyelinationAutores:Alexey Llópiz-Arzuaga, Bergami A., Fernández-Massó J.R., Furlan R., Herrera-Rolo T., Lagumersindez-Denis N., Marín-Prida J., Muzio L., Nazabal-Galvez M., Pentón-Arias E., Pentón-Rol G., Polentarutti N., Raíces-Cruz I., Teixeira M.M., Valenzuela-Silva C.M., Veliz-Rodriguez T.Fuentes:googlescopusC-Phycocyanin ameliorates experimental autoimmune encephalomyelitis and induces regulatory T cells
ArticleAbstract: For decades Experimental Autoimmune Encephalitis (EAE) has remained as an unsurpassed multiple sclerPalabras claves:Central nervous system, Demyelination, Multiple Sclerosis, Neurodegenerative disorder, Regulatory T cellsAutores:Acosta-Medina E.F., Alexey Llópiz-Arzuaga, Alonso-Ramírez R., Cervantes-Llanos M., Falcón-Cama V., Guillén-Nieto G.E., Lagumersindez-Denis N., López-Saura P.A., Marín-Prida J., Martínez-Sánchez G., Pentón-Arias E., Pentón-Rol G., Rodríguez-Jiménez E., Valenzuela-Silva C.M.Fuentes:googlescopusC-Phycocyanin is neuroprotective against global cerebral ischemia/reperfusion injury in gerbils
ArticleAbstract: Although the huge economic and social impact and the pbkp_redicted incidence increase, neuroprotectiPalabras claves:antioxidant, C-Phycocyanin, Gerbil, Global cerebral ischemia/reperfusion, neuroprotectionAutores:Acosta-Medina E.F., Alexey Llópiz-Arzuaga, Guillén-Nieto G.E., Lagumersindez-Denis N., López-Saura P.A., Marín-Prida J., Martínez-Sánchez G., Pardo-Andreu G.L., Pentón-Arias E., Pentón-Rol G., Rodríguez-Jiménez E., Valdivia-Acosta A.Fuentes:googlescopusC-Phycocyanin protects SH-SY5Y cells from oxidative injury, rat retina from transient ischemia and rat brain mitochondria from Ca<sup>2+</sup>/phosphate-induced impairment
ArticleAbstract: Oxidative stress and mitochondrial impairment are essential in the ischemic stroke cascade and eventPalabras claves:antioxidant, C-Phycocyanin, neuroprotection, Rat brain mitochondria, SH-SY5Y, Transient rat retinal ischemiaAutores:Alberici L.C., Alexey Llópiz-Arzuaga, Curti C., Leopoldino A.M., Liberato J.L., Marín-Prida J., Naal Z., Pardo-Andreu G.L., Pentón-Arias E., Pentón-Rol G., Polizello A.C.M., Rodrigues F.P., Rosa M.N., Santos W.F.d., Stringhetta K., Uyemura S.A.Fuentes:googlescopusNovel Insights into the Molecular Mechanisms Involved in the Neuroprotective Effects of C-Phycocyanin against Brain Ischemia in Rats
ArticleAbstract: Background: Ischemic stroke produces a large health impact worldwide, with scarce therapeutic optionPalabras claves:Brain ischemia, C-Phycocyanin, Ischemic stroke, NADPH oxidase, neuroinflammation, neuroprotectionAutores:Alexey Llópiz-Arzuaga, Antoni Camins, Cruz O.G., González I.H., Leopoldino A.M., Liberato J.L., Marín-Prida J., Pardo-Andreu G.L., Pavón-Fuentes N., Pentón-Rol G., Pérez M.L., Santos W.F.D., Stringhetta-Padovani K., Uyemura S.A.Fuentes:googlescopusPhycocyanobilin promotes PC12 cell survival and modulates immune and inflammatory genes and oxidative stress markers in acute cerebral hypoperfusion in rats
ArticleAbstract: Since the inflammatory response and oxidative stress are involved in the stroke cascade, we evaluatePalabras claves:Cerebral hypoperfusion, Gene Expression, inflammation, Oxidative Stress, PC12, phycocyanobilinAutores:Alexey Llópiz-Arzuaga, Cintado-Benítez A., Cruz-Ramírez A., Fernández-Massó J.R., Marín-Prida J., Mendoza-Marí Y., Nazabal-Galvez M., Pardo-Andreu G.L., Pavón-Fuentes N., Pentón-Arias E., Pentón-Rol G., Polentarutti N., Riva F., Roche L.D., Santana S.P., Valenzuela-Silva C.M.Fuentes:googlescopusPhycocyanobilin reduces brain injury after endothelin-1- induced focal cerebral ischaemia
ArticleAbstract: Pharmacological therapies for interrupting biochemical events of the ischaemic cascade and protectinPalabras claves:Ischaemic stroke, neuroprotection, PC12, phycocyanobilinAutores:Alexey Llópiz-Arzuaga, Campos-Mojena R., Cervantes-Llanos M., Falcón-Cama V., Marín-Prida J., Pavón-Fuentes N., Pentón-Arias E., Pentón-Rol G., Piniella-Matamoros B.Fuentes:scopusProtective effects of C-Phycocyanin against lipid peroxidation of serum lipoproteins and hepatic microsomes
ArticleAbstract: Lipid peroxidation has been considered as deleterious phenomenon associated with diseases such as atPalabras claves:Antioxidant capacity, C-Phycocyanin, Lipid peroxidation, Oxidative StressAutores:Alexey Llópiz-Arzuaga, Denis N.L., Pentón-Arias E., Pentón-Rol G., Roche L.D.Fuentes:googlescopus