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A novel functional cell surface dimer (Kp43) expressed by natural killer cells and T cell receptor-γ/δ<sup>+</sup> T lymphocytes. I. Inhibition of the IL-2-dependent proliferation by anti-Kp43 monoclonal antibody
ArticleAbstract: In the present study we describe a novel functional cell surface molecule, designated as Kp43, whichPalabras claves:Autores:Acevedo A., Aramburu J., Balboa M.A., López‐Botet M., Manuel Ortiz de Landázuri, Ramirez A., Sánchez‐Madrid F., SILVA A.G.Fuentes:scopusCostimulation of cAMP and protein kinase C pathways inhibits the cd3-dependent t cell activation and leads to a persistent expression of the AP-1 transcription factor
ArticleAbstract: The effects mediated by a combined stimulation of cAMP- and protein kinase C (PKC)-dependent pathwayPalabras claves:Autores:López‐Botet M., Manuel Ortiz de Landázuri, Rincon M., Tugores A.Fuentes:scopusDefective interleukin 2 receptor expression is associated with the T cell disfunction subsequent to bone marrow transplantation
ArticleAbstract: In the present work we have used monoclonal antibodies (mAb) as probes to attempt a dissection of thPalabras claves:Autores:Cámara R., Fernández‐Rañada J., Figuera A., Izquierdo M., López‐Botet M., Manuel Ortiz de Landázuri, Ramirez A.Fuentes:scopusCD2 is involved in regulating cyclic AMP levels in T cells
ArticleAbstract: The human T lymphocyte‐specific CD2 (T11) molecule, that regulates T cell activation, is capable ofPalabras claves:Autores:Carrera A.C., López‐Botet M., Manuel Ortiz de Landázuri, Rincon M.Fuentes:scopusGeneration of T cell blasts with NK-like activity in human MLC: Cellular precursors, IL 2 responsiveness, and phenotype expression
ArticleAbstract: Human MLC were separated after 5 to 7 days of culture by Percoll density gradient centrifugation intPalabras claves:Autores:López‐Botet M., Manuel Ortiz de Landázuri, Rodiguez J., SILVA A.G.Fuentes:scopusExpression of a gp33/27,000 MW activation inducer molecule (AIM) on human lymphoid tissues. Induction of cell proliferation on thymocytes and B lymphocytes by anti-AIM antibodies
ArticleAbstract: We have recently described several monoclonal antibodies (mAb) that recognize a heterodimeric structPalabras claves:Autores:Acevedo A., Cebrian M., López‐Botet M., Manuel Ortiz de Landázuri, Sánchez‐Madrid F., Sánchez‐Mateos P.Fuentes:scopusExpression of a novel activation antigen on intrahepatic CD8<sup>+</sup> T lymphocytes in viral chronic active hepatitis
ArticleAbstract: It has been suggested that CD8+ T lymphocytes play an important role in the pathogenesis of liver cePalabras claves:Autores:García-Monzón C., García-Sánchez A., López‐Botet M., Manuel Ortiz de Landázuri, Moreno-Otero R., Pajares J.M., Sánchez‐Madrid F.Fuentes:scopusHuman large granular lymphocytes: Spontaneous and interferon-boosted NK activity against adherent and nonadherent tumor cell lines
ArticleAbstract: Human natural killer (NK) cells against K-562 tumor cells have been morphologically identified as laPalabras claves:Autores:Herberman R.B., López‐Botet M., Manuel Ortiz de Landázuri, Ortaldo J.R., Timonen T.Fuentes:scopusIn vitro immune cell function in six cases of immunoproliferative small intestine disease after long term remission
ArticleAbstract: We have studied several parameters of in vitro immune cell function in peripheral blood mononuclearPalabras claves:Autores:Abreu L., Chantar C., Kreisler M., López‐Botet M., Manuel Ortiz de Landázuri, Plaza A.Fuentes:scopusInduction of natural killer‐like cytotoxicity in cultured human thymocytes
ArticleAbstract: Supernatants containing interleukin 2 (IL2) induce strong proliferation and expression of natural kiPalabras claves:Autores:López‐Botet M., Manuel Ortiz de Landázuri, Toribio M.L.Fuentes:scopus