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A novel biparatopic hybrid antibody-ACE2 fusion that blocks SARS-CoV-2 infection: implications for therapy
ArticleAbstract: In the absence of a proven effective vaccine preventing infection by SARS-CoV-2, or a proven drug toPalabras claves:antibody-ACE2 fusion, Biparatopic, covid-19, neutralizing antibody, SARS-COV-2Autores:Chen C., Chen L., Fu W., Gao W., Huang X., James W.S., Javier Gilbert Jaramillo, Jiang W., Knight M.L., Lee S.M.Y., Liu X., Luo Y., Miao X., Pang T., Rijal P., Song X., Sun J., Tan T.K., Tang Y., Townsend A.R., Tsun A., Wan L., Wang C., Wu F., Xu Y., Yan Y., Yuan Z., Zou Y.Fuentes:scopusNeutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2
ArticleAbstract: The SARS-CoV-2 virus is more transmissible than previous coronaviruses and causes a more serious illPalabras claves:Autores:Buttigieg K.R., Carrique L., Carroll M.W., Clare D.K., Coombes N., Dumoux M., Duyvesteyn H.M.E., Elmore M.J., Harrison P.J., Huo J., James W.S., Javier Gilbert Jaramillo, Knight M.L., Le Bas A., Malinauskas T., Mikolajek H., Moynié L., Naismith J.H., Owens R.J., Radecke J., Ren J., Rijal P., Ruza R.R., Shah P.N.M., Stuart D.I., Tan T.K., Townsend A.R., Tree J.A., Vogirala V.K., Ward P.N., Weckener M., Zhao Y., Zhou D.Fuentes:scopusSARS-CoV-2 RNA detected in blood products from patients with COVID-19 is not associated with infectious virus
ArticleAbstract: Background: Laboratory diagnosis of SARS-CoV-2 infection (the cause of COVID-19) uses PCR to detectPalabras claves:Biomarker, Blood, covid-19, Laboratory safety, RNA, SARS-COV-2, Viraemia, Viral loadAutores:Andersson M.I., Arancibia-Cárcamo C.V., Auckland K., Baillie J.K., Barnes E., Beneke T., Bibi S., Brooks T.J.G., Carroll M.W., Crook D.W., Dingle K., Dold C., Downs L.O., Dunn L., Eyre D.W., Harvala H., Hoosdally S., Ijaz S., James T., James W.S., Javier Gilbert Jaramillo, Jeffery K., Justice A., Klenerman P., Knight J.C., Knight M.L., Liu X., Lumley S.F., Matthews P.C., McNaughton A.L., Mentzer A.J., Mongkolsapaya J., Oakley S., Oliveira M.S., Peto T., Ploeg R.J., Ratcliff J., Robbins M.J., Roberts D.J., Rudkin J., Russell R.A., Screaton G.R., Semple M.G., Simmonds P., Skelly D.T., Stoesser N., Turtle L., Wareing S., Zambon M.Fuentes:scopusStructural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient
ArticleAbstract: The COVID-19 pandemic has had an unprecedented health and economic impact and there are currently noPalabras claves:Autores:Buttigieg K.R., Carrique L., Carroll M.W., Chen C.P., Chen T.H., Cheng C.Y., Cheng S.H., Donat R.F., Duyvesteyn H.M.E., Fry E.E., Godwin K., Huang C.G., Huang K.Y.A., Huang Y.C., Huo J., James W.S., Javier Gilbert Jaramillo, Knight M.L., Lin T.Y., Lin Y.C., Ma C., Malinauskas T., Mongkolsapaya J., Naismith J.H., Owens R.J., Paterson N.G., Radecke J., Ren J., Rijal P., Ruza R.R., Screaton G.R., Shah P.N.M., Shih S.R., Stuart D.I., Supasa P., Tan T.K., Townsend A.R., Tree J.A., Zhao Y., Zhou D.Fuentes:scopus