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scopus(16)
Defeating Leishmania resistance to Miltefosine (hexadecylphosphocholine) by peptide-mediated drug smuggling: A proof of mechanism for trypanosomatid chemotherapy
ArticleAbstract: Miltefosine (hexadecylphosphocholine, HePC), the first orally active drug successful against leishmaPalabras claves:cell-penetrating peptide, LEISHMANIA, Miltefosine, Resistance reversion, Tat, TrypanosomaAutores:Acuña A.U., Amat-Guerri F., Andreu D., B. G. De la Torre, Bart J.M., Hornillos V., Luque-Ortega J.R., Navarro M., Rivas L., Rueda C.Fuentes:scopusDendrimeric peptides can confer protection against foot-and-mouth disease virus in cattle
ArticleAbstract: Foot-and-mouth disease virus (FMDV) causes a highly contagious disease in cloven-hoofed animals. A sPalabras claves:Autores:Andreu D., B. G. De la Torre, Blanco E., Digiacomo S., Gammella M., Langellotti C., Montoya M., Quattrocchi V., Sobrino F., Soria I., Zamorano P.Fuentes:scopusCyclic amino acid linkers stabilizing key loops of brain derived neurotrophic factor
ArticleAbstract: Based on β-turn-like BDNF loops 2 and 4, involved in receptor interaction, cyclic peptide replicas wPalabras claves:BDNF, Growth factors, Peptides, Secondary peptide structure mimetics, β-TurnAutores:Almeida R.D., Andreu D., B. G. De la Torre, Baeza J.L., Garcı́a-López M.T., Gerona-Navarro G., Gonzalez-Muniz R., Jaffrey S.R., Jiménez M.A., Martín-Martínez M., Santiveri C.M.Fuentes:scopusA BODIPY-embedding miltefosine analog linked to cell-penetrating Tat(48-60) peptide favors intracellular delivery and visualization of the antiparasitic drug
ArticleAbstract: Therapeutic application of many drugs is often hampered by poor or denied access to intracellular taPalabras claves:BODIPY, cell-penetrating peptide, Dual fluorescent labeling, Miltefosine, Monitoring of intracellular drug delivery, Reversion of resistanceAutores:Abengózar M.Á., Amat-Guerri F., Andreu D., B. G. De la Torre, Hornillos V., Luque-Ortega J.R., Rivas L., Ulises Acuña A.Fuentes:scopusA T-cell epitope on NS3 non-structural protein enhances the B and T cell responses elicited by dendrimeric constructions against CSFV in domestic pigs
ArticleAbstract: It has been recently reported by our group that dendrimeric constructs combining B- and T-cell epitoPalabras claves:Cellular and humoural immune response, Classical swine fever virus, Dendrimeric peptide vaccine, Epitopes, Marker (DIVA) vaccineAutores:Andreu D., B. G. De la Torre, Domingo M., Fraile L., Ganges L., Monsó M., Muñoz M., Nofrarías M., Pérez L.J., Riquelme C., Rosell R., Sobrino F., Tarradas J.Fuentes:scopusB epitope multiplicity and B/T epitope orientation influence immunogenicity of foot-and-mouth disease peptide vaccines
ArticleAbstract: Synthetic peptides incorporating protective B- and T-cell epitopes are candidates for new safer footPalabras claves:Autores:Andreu D., B. G. De la Torre, Bárcena J., Blanco E., Cubillos C., Moreno N., Sobrino F.Fuentes:scopusInclusion of a specific T cell epitope increases the protection conferred against foot-and-mouth disease virus in pigs by a linear peptide containing an immunodominant B cell site
ArticleAbstract: Background. Foot-and-mouth disease virus (FMDV) causes an economically important and highly contagioPalabras claves:FMDV, foot-and-mouth disease virus, Linear peptides, pig, Swine, VaccineAutores:Andreu D., B. G. De la Torre, Bárcena J., Blanco E., Cubillos C., Sobrino F.Fuentes:scopusInfluence of conjugation chemistry and B epitope orientation on the immune response of branched peptide antigens
ArticleAbstract: Multimeric presentation, a well-proven way of enhancing peptide immunogenicity, has found substantiaPalabras claves:Autores:Andreu D., B. G. De la Torre, Blanco E., Monsó M., Moreno N.Fuentes:scopusMembrane-transferring Sequences of the HIV-1 Gp41 Ectodomain Assemble into an Immunogenic Complex
ArticleAbstract: The membrane-proximal stem region of gp41 has been postulated to host the two conserved membrane-traPalabras claves:2F5 antibody, gp41, gp41 pre-transmembrane, HIV-1, HIV-1 fusion peptideAutores:Andreu D., B. G. De la Torre, Gómara M.J., Lorizate M., Nieva J.L.Fuentes:scopusPeptide vaccine candidates against classical swine fever virus: T cell and neutralizing antibody responses of dendrimers displaying E2 and NS2-3 epitopes
ArticleAbstract: Three peptide-based systems integrating B and T antigenic sites of CSFV and displaying the B epitopePalabras claves:classical swine fever, Dendrimeric peptides, PEG-like flexibilizing units, Peptide vaccinesAutores:Andreu D., B. G. De la Torre, Ganges L., Monsó M., Sobrino F., Tarradas J.Fuentes:scopus