Mostrando 10 resultados de: 55
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Journal of Medicinal Chemistry(6)
Journal of Peptide Science(4)
Amino Acids(3)
Bioconjugate Chemistry(3)
Bioorganic and Medicinal Chemistry Letters(3)
Área temáticas
Farmacología y terapéutica(29)
Microorganismos, hongos y algas(20)
Bioquímica(18)
Enfermedades(17)
Química orgánica(9)
Enhanced mucosal immunoglobulin A response and solid protection against foot-and-mouth disease virus challenge induced by a novel dendrimeric peptide
ArticleAbstract: The successful use of a dendrimeric peptide to protect pigs against challenge with foot-and-mouth diPalabras claves:Autores:Andreu D., B. G. De la Torre, Bárcena J., Blanco E., Borrás E., Clementi G., Cubillos C., Jakab A., Sobrino F.Fuentes:scopusEssential Role of Enzymatic Activity in the Leishmanicidal Mechanism of the Eosinophil Cationic Protein (RNase 3)
ArticleAbstract: The recruitment of eosinophils into Leishmania lesions is frequently associated with a favorable evoPalabras claves:Antimicrobial peptide, cell-penetrating enzyme, membrane disruption, protozoa, RNaseAutores:Abengózar M.Á., Andreu D., B. G. De la Torre, Boix E., Fernández-Reyes M., Rivas L., Salazar V.A., Torrent M.Fuentes:scopusFull protection of swine against foot-and-mouth disease by a bivalent B-cell epitope dendrimer peptide
ArticleAbstract: Foot-and-mouth disease virus (FMDV) causes a highly contagious disease of cloven-hoofed animals. WePalabras claves:foot-and-mouth disease virus, Peptide dendrimers, PROTECTION, vaccinesAutores:Andreu D., B. G. De la Torre, Blanco E., Defaus S., Dekker A., Guerra B., Sobrino F.Fuentes:scopusDefeating Leishmania resistance to Miltefosine (hexadecylphosphocholine) by peptide-mediated drug smuggling: A proof of mechanism for trypanosomatid chemotherapy
ArticleAbstract: Miltefosine (hexadecylphosphocholine, HePC), the first orally active drug successful against leishmaPalabras claves:cell-penetrating peptide, LEISHMANIA, Miltefosine, Resistance reversion, Tat, TrypanosomaAutores:Acuña A.U., Amat-Guerri F., Andreu D., B. G. De la Torre, Bart J.M., Hornillos V., Luque-Ortega J.R., Navarro M., Rivas L., Rueda C.Fuentes:scopusDendrimeric peptides can confer protection against foot-and-mouth disease virus in cattle
ArticleAbstract: Foot-and-mouth disease virus (FMDV) causes a highly contagious disease in cloven-hoofed animals. A sPalabras claves:Autores:Andreu D., B. G. De la Torre, Blanco E., Digiacomo S., Gammella M., Langellotti C., Montoya M., Quattrocchi V., Sobrino F., Soria I., Zamorano P.Fuentes:scopusConformational analysis of peptides and glycopeptides derived from the consensus sequence for β-O-glucosylation
ArticleAbstract: Cys-Xxx-Ser-Xxx-Pro-Cys (Xxx= any amino acid but Pro) is the most common sequence present in naturalPalabras claves:Conformational analysis, molecular dynamics, Nuclear magnetic resonance, β-O-glucosylationAutores:Andreu D., Asensio J.L., Avenoza A., B. G. De la Torre, Busto J.H., Corzana F., Fernández-Tejada A., Jiménez-Barbero J., Martínez-Sáez N., Peregrina J.M., Somovilla V.J.Fuentes:scopusEfficacy of cecropin A-melittin peptides on a sepsis model of infection by pan-resistant Acinetobacter baumannii
ArticleAbstract: Pan-resistant Acinetobacter baumannii have prompted the search for therapeutic alternatives. We evalPalabras claves:Autores:Andreu D., B. G. De la Torre, Bengoechea J.A., Docobo-Pérez F., Fernández-Reyes M., López-Rojas R., March C., Pachón J., Pachón-Ibañez M.E., Rivas L.Fuentes:scopusEfficient cellular delivery of β-galactosidase mediated by NrTPs, a new family of cell-penetrating peptides
ArticleAbstract: Nucleolar targeting peptides (NrTPs), a recently developed family of cell-penetrating peptides, havePalabras claves:Autores:Andreu D., B. G. De la Torre, Rádis-Baptista G., Rodrigues M., Santos N.C.Fuentes:scopusCyclic amino acid linkers stabilizing key loops of brain derived neurotrophic factor
ArticleAbstract: Based on β-turn-like BDNF loops 2 and 4, involved in receptor interaction, cyclic peptide replicas wPalabras claves:BDNF, Growth factors, Peptides, Secondary peptide structure mimetics, β-TurnAutores:Almeida R.D., Andreu D., B. G. De la Torre, Baeza J.L., Garcı́a-López M.T., Gerona-Navarro G., Gonzalez-Muniz R., Jaffrey S.R., Jiménez M.A., Martín-Martínez M., Santiveri C.M.Fuentes:scopusA BODIPY-embedding miltefosine analog linked to cell-penetrating Tat(48-60) peptide favors intracellular delivery and visualization of the antiparasitic drug
ArticleAbstract: Therapeutic application of many drugs is often hampered by poor or denied access to intracellular taPalabras claves:BODIPY, cell-penetrating peptide, Dual fluorescent labeling, Miltefosine, Monitoring of intracellular drug delivery, Reversion of resistanceAutores:Abengózar M.Á., Amat-Guerri F., Andreu D., B. G. De la Torre, Hornillos V., Luque-Ortega J.R., Rivas L., Ulises Acuña A.Fuentes:scopus