Documentos de López-Querol M. | REDI

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Mostrando 4 resultados de: 4

Subtipo de publicación

Publisher

Bioorganic and Medicinal Chemistry(2)

NeuroToxicology(1)

Toxicology in Vitro(1)

Área temáticas

Enfermedades(2)

Farmacología y terapéutica(2)

Fisiología humana(2)

Fisiología y materias afines(2)

Área de conocimiento

Farmacología(2)

Descubrimiento de fármacos(1)

Expresión génica(1)

Año de Publicación

Origen

Palabras Claves

Acute toxicity(2)

Cerebellar granule neurons(2)

Oxidative Stress(2)

Evaluation of pathways involved in pentachlorophenol-induced apoptosis in rat neurons

Abstract: Pentachlorophenol (PCP) (C6HCl5O) is a synthetic toxic organochloride fungicide for humans which exh

Palabras claves:

Acute toxicity, apoptosis, caspase, cell cycle, Cerebellar granule neurons, Oxidative Stress, Pentachlorophenol

Alvira D., Antoni Camins, Bordas M., de la Torre A.V., Folch J., López-Querol M., Pallás M., Rimbau V., Sureda F.X., Yeste-Velasco M.

Evaluation of transcriptional activity of caspase-3 gene as a marker of acute neurotoxicity in rat cerebellar granular cells

Abstract: Caspase-3 is a key protein involved in the classical apoptosis mechanism in neurons, as in many othe

Palabras claves:

Acute toxicity, apoptosis, Caspase-3, Cell-cycle, Cerebellar granule neurons, Oxidative Stress

Alvira D., Antoni Camins, Folch J., Forsby A., López-Querol M., Pallás M., Rimbau V., Sureda F.X., Tajes M.

New oxapolycyclic cage amines with NMDA receptor antagonist and trypanocidal activities

Abstract: The synthesis of several (1,2,3,5,6,7-hexahydro-1,5:3,7-dimethano-4-benzoxonin-3-yl)amines and relat

Palabras claves:

Amantadine, Indantadol, Memantine, NGP1-01, NMDA, Polycyclic cage compounds, Trypanosoma

Antoni Camins, Camps P., Duque M.D., Kelly J.M., López-Querol M., Prathalingam S.R., Sureda F.X., Torres E., Valverde E., Vázquez S.

Synthesis and pharmacological evaluation of several ring-contracted amantadine analogs

Abstract: The synthesis of several (3-noradamantyl)amines, [(3-noradamantyl)methyl]amines, (3,7-dimethyl-1-bis

Palabras claves:

Amantadine, influenza, Memantine, NMDA receptor antagonist, Polycyclic cage compounds, Trypanosomiasis

Antoni Camins, Camps P., Cortés D., De Clercq E., Duque M.D., Ivorra D., Kelly J.M., López-Querol M., Naesens L., Pallás M., Prathalingam S.R., Romero V., Sureda F.X., Vázquez S.