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scopus(8)
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation
ArticleAbstract: Pyrin responds to pathogen signals and loss of cellular homeostasis by forming an inflammasome complPalabras claves:Autores:Amselem S., Baker P.J., Cochet E., Copin B., Dagley L.F., De Nardo D., De Somer L., Dooley J., Goris A., Holley C.L., Jeandel P.Y., Jéru I., Josselyn E. Garcia-Perez, Lagou V., Lawless D., Liston A., Lyras D., Masters S.L., Medlej-Hashim M., Megarbane A., Moghaddas F., Nicholson S.E., Parry D.A., Pasciuto E., Ruuth-Praz J., Savic S., Schroder K., Sciot R., Van Eyck L., Van Nieuwenhove E., Webb A.I., Wouters C.H.Fuentes:scopusGenetic Architecture of Adaptive Immune System Identifies Key Immune Regulators
ArticleAbstract: The immune system is highly diverse, but characterization of its genetic architecture has lagged behPalabras claves:adaptive immune system, association, autoimmunity, Genetics, Genome-wide association, immune phenotype, susceptibilityAutores:Boeckxstaens G., Bowness P., Chen L., Dooley J., Dubois B., Goris A., Hilven K., Humblet-Baron S., Josselyn E. Garcia-Perez, Lagou V., Liston A., Mallants K., Moisse M., Prezzemolo T., Smets I., Van Damme P., Van Horebeek L., Vandebergh M.Fuentes:scopusGenetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes
ArticleAbstract: Type 1 (T1D) and type 2 (T2D) diabetes share pathophysiological characteristics, yet mechanistic linPalabras claves:Autores:Allemeersch J., Carr E.J., Chabot-Roy G., Dahlstrom J.E., Delghingaro-Augusto V., Di Marino D., Dooley J., Franckaert D., Gevaert K., Goodnow C.C., Jetten A.M., Josselyn E. Garcia-Perez, Lagou V., Lambrechts D., Laybutt D.R., Lesage S., Linterman M.A., Liston A., Lyssenko V., Nolan C.J., Oskolkov N., Overbergh L., Pasciuto E., Petrovsky N., Schlenner S.M., Schönefeldt S., Socha L., Tian L., Vandenbussche J.Fuentes:scopusA kindred with mutant IKAROS and autoimmunity
ArticleAbstract:Palabras claves:Autores:Claessens F., Dooley J., Frietze S., Gijsbers R., Helsen C., Humblet-Baron S., Josselyn E. Garcia-Perez, Liston A., Meyts I., Rodriguez P.D., Schjerven H., Schlenner S.M., van der Burg M., Van Nieuwenhove E., van Schouwenburg P.A., Verhoeyen E., Wouters C.H.Fuentes:scopusAuthor Correction: The cellular composition of the human immune system is shaped by age and cohabitation (Nature Immunology, (2016), 17, 4, (461-468), 10.1038/ni.3371)
OtherAbstract: In the version of this article initially published, in the Acknowledgements, the grant number for thPalabras claves:Autores:Boeckxstaens G., Carr E.J., Dooley J., Goris A., Josselyn E. Garcia-Perez, Lagou V., Lee J.C., Linterman M.A., Liston A., Meyts I., Wouters C.H.Fuentes:scopusImmunologic profiles of multiple sclerosis treatments reveal shared early B cell alterations
ArticleAbstract: Objective: We undertook a systems immunology approach of the adaptive immune system in multiple sclePalabras claves:Autores:Danso-Abeam D., de Muynck L., Decallonne B., Dooley J., Dubois B., Franckaert D., Goris A., Hilven K., Josselyn E. Garcia-Perez, Liston A., Nguyen A.T.L., Pauwels I., Smets I., Terbeek J.Fuentes:scopusMultiple sclerosis risk variants alter expression of co-stimulatory genes in B cells
ArticleAbstract: The increasing evidence supporting a role for B cells in the pathogenesis of multiple sclerosis promPalabras claves:B cells, CD40, CD86, Multiple Sclerosis, susceptibilityAutores:Ban M., Coles A.J., Compston A., Dooley J., Dubois B., Fiddes B., Goris A., He D., Humblet-Baron S., Jones J., Josselyn E. Garcia-Perez, Liao W., Liston A., Mallants K., Sawcer S., Smets I., Wang G.Fuentes:scopusmiR-29a-deficiency does not modify the course of murine pancreatic acinar carcinoma
ArticleAbstract: The development of cancers involves the complex dysregulation of multiple cellular processes. With kPalabras claves:In vivo, microRNA, MiR-29, pancreatic cancerAutores:Dooley J., Himmelreich U., Josselyn E. Garcia-Perez, Lagou V., Liston A.Fuentes:scopus