Mostrando 10 resultados de: 11
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Annals of the New York Academy of Sciences(1)
Apoptosis(1)
Biochemical Pharmacology(1)
Bipolar Disorders(1)
Brain Research(1)
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Farmacología y terapéutica(6)
Bioquímica(3)
Sistemas fisiológicos específicos de los animales(3)
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Fisiología y materias afines(2)
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scopus(11)
(±)-huprine Y, (-)-huperzine A and tacrine do not show neuroprotective properties in an apoptotic model of neuronal cytoskeletal alteration
ArticleAbstract: Acetylcholinesterase inhibitors (AChEI) are among the drugs most widely used in the treatment of AlzPalabras claves:acetylcholinesterase inhibitors, Cerebellar granule cells, colchicine, neuronal death, RATAutores:Antoni Camins, Camps P., Canudas A.M., Jiménez A., Jordá E.G., Muñoz-Torrero D., Pallás M., Rimbau V., Verdaguer E.Fuentes:scopusCyclosporin A enhances colchicine-induced apoptosis in rat cerebellar granule neurons
ArticleAbstract: 1 Cyclosporin A (CsA, 1-50 μM), an immunosuppressive drug with known neurotoxic effects, did not decPalabras claves:CDK5, colchicine, Cyclosporin A, flavopiridol, Neurotoxicity, RoscovitineAutores:Antoni Camins, Canudas A.M., Jiménez A., Jordá E.G., Pallás M., Rimbau V., Sureda F.X., Verdaguer E.Fuentes:scopusFlavopiridol: An antitumor drug with potential application in the treatment of neurodegenerative diseases
ArticleAbstract: Several lines of evidence show that cyclin-dependent kinases (CDKs) contribute to neurodegenerativePalabras claves:Autores:Antoni Camins, Canudas A.M., Jiménez A., Jordá E.G., Pallás M., Verdaguer E.Fuentes:scopusEvaluation of the neuronal apoptotic pathways involved in cytoskeletal disruption-induced apoptosis
ArticleAbstract: The cytoskeleton is critical to neuronal functioning and survival. Cytoskeletal alterations are invoPalabras claves:calcium, Calpainsl, Caspases, Cytoskeleton, Serine-proteasesAutores:Allgaier C., Antoni Camins, Arriba S.G.D., Jiménez A., Jordá E.G., Pallás M., Verdaguer E.Fuentes:scopusEvidence in favour of a role for peripheral-type benzodiazepine receptor ligands in amplification of neuronal apoptosis
ArticleAbstract: The mitochondrial peripheral benzodiazepine receptor (PBR) is involved in a functional structure desPalabras claves:AIF, Cerebellar granule cells, colchicine, Cyt c, Mitochondrial permeability transition, Peripheral benzodiazepine receptorAutores:Antoni Camins, Canudas A.M., Folch J., Jiménez A., Jordá E.G., Pallás M., Sureda F.X., Verdaguer E.Fuentes:scopusNeuroprotective action of flavopiridol, a cyclin-dependent kinase inhibitor, in colchicine-induced apoptosis
ArticleAbstract: Flavopiridol was developed as a drug for cancer therapy due to its ability to inhibit cell cycle proPalabras claves:Caspase-3, Cerebellar granule neurons, Cyclin-dependent kinases, flavopiridol, neuroprotection, Par-4Autores:Antoni Camins, Bravo R., Bruna A., Caelles C., Camarasa J., Canudas A.M., Escubedo E., Jiménez A., Jordá E.G., Pallás M., Pubill D., Verdaguer E.Fuentes:scopusImplication of cyclin-dependent kinase 5 in the neuroprotective properties of lithium
ArticleAbstract: Although numerous studies have demonstrated a neuroprotective and anti-apoptotic role of lithium inPalabras claves:apoptosis, Cdk5/p25, Cerebellar granule neurons, GSK-3β, LithiumAutores:Allgaier C., Antoni Camins, Canudas A.M., Garcia De Arriba S., Jiménez A., Jordá E.G., Pallás M., Verdaguer E.Fuentes:scopusInhibition of CDKs: A Strategy for Preventing Kainic Acid-Induced Apoptosis in Neurons
Conference ObjectAbstract: Stimulation of ionotropic glutamate receptors are implicated in neurodegenerative diseases such as APalabras claves:3-ATA, Cdk, Cerebellar granule cells, flavopiridol, Kainic acidAutores:Antoni Camins, Canudas A.M., Jiménez A., Jordá E.G., Pallás M., Stranges A., Sureda F.X., Verdaguer E.Fuentes:scopusInhibition of multiple pathways accounts for the antiapoptotic effects of flavopiridol on potassium withdrawal-induced apoptosis in neurons
ArticleAbstract: Serum and potassium (S/K) deprivation is a well-known apoptotic model in cerebellar granule neuronsPalabras claves:apoptosis, Cdk, cell cycle, flavopiridol, GSK-3β, MEF2Autores:Alvira D., Antoni Camins, Canudas A.M., Folch J., Jiménez A., Jordá E.G., Pallás M., Rimbau V., Verdaguer E.Fuentes:scopusLithium prevents colchicine-induced apoptosis in rat cerebellar granule neurons
ArticleAbstract: Objectives: Here we evaluated the neuroprotective effects of two well-known mood stabilizers, lithiuPalabras claves:apoptosis, colchicine, Lithium, neuroprotectionAutores:Antoni Camins, Canudas A.M., Jiménez A., Jordá E.G., Morano A., Pallás M., Verdaguer E.Fuentes:scopus