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Experimental and theoretical reduction potentials of some biologically active ortho-carbonyl para-quinones
ArticleAbstract: The rational design of quinoneswith specific redox properties is an issue of great interest becausePalabras claves:Cyclic Voltammetry, density functional theory, Quinones, Redox potential, SemiquinoneAutores:Araya-Maturana R., Martínez-Cifuentes M., Oney O. Ramírez-Rodríguez, Salazar R., Weiss-López B.Fuentes:scopusEffects of simple and angular chromones on tumor cell respiration
ArticleAbstract: A set of structurally related compounds incorporating a chromone moiety as an essential component ofPalabras claves:Cáncer, Cell respiration, ChromoneAutores:Araya-Maturana R., Donoso-Tauda O., Ferreira J., Hernández J.T., Jorge Hebkp_redia-Moya, Pavani M., Pessoa-Mahana H., Vera M., Weiss-López B.Fuentes:googlescopusNMR assignment in regioisomeric hydroquinones
ArticleAbstract: A set of regioisomeric pairs of tricyclic hydroquinones, analogues of antitumor 9,10-dihydroxy-4,4-dPalabras claves:1 H NMR, 13 C NMR, 3 J H H, Alhrichs-pVTZ, DFT, GIAO, HMBC, HMQC, Hydroquinone, O3LYPAutores:Araya-Maturana R., Calvo-Flores F.G., Cardona W., Dobado J.A., Gómez-Tamayo J.C., Martínez-García H., Oney O. Ramírez-Rodríguez, Pessoa-Mahana H., Weiss-López B.Fuentes:scopusMitochondria: A promising target for anticancer alkaloids
ArticleAbstract: A great number of alkaloids exhibit high potential in cancer research. Some of them are anticancer dPalabras claves:alkaloids, apoptosis, Cancer cells, DELIVERY, Endoplasmic reticulum, Mitochondria, targetingAutores:Araya-Maturana R., Córdova-Delgado M., Ferreira J., Oney O. Ramírez-Rodríguez, Pessoa-Mahana H., Urra F.A., Weiss-López B.Fuentes:scopusSmall structural changes on a hydroquinone scaffold determine the complex I inhibition or uncoupling of tumoral oxidative phosphorylation
ArticleAbstract: Mitochondria participate in several distinctiveness of cancer cell, being a promising target for thePalabras claves:Anti-cancer agents, Complex I, Hydroquinones, Oxidative phosphorylation, UncouplersAutores:Acevedo-Arévalo L., Andrea Orellana Manzano, Araya-Maturana R., Córdova-Delgado M., Ferreira J., González-Vivanco J.M., Lapier M., Martínez-Cifuentes M., Millas-Vargas J.P., Oney O. Ramírez-Rodríguez, Pavani M., Pessoa-Mahana H., Urra F.A., Weiss-López B.Fuentes:scopus