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Cyclosporin A enhances colchicine-induced apoptosis in rat cerebellar granule neurons
ArticleAbstract: 1 Cyclosporin A (CsA, 1-50 μM), an immunosuppressive drug with known neurotoxic effects, did not decPalabras claves:CDK5, colchicine, Cyclosporin A, flavopiridol, Neurotoxicity, RoscovitineAutores:Antoni Camins, Canudas A.M., Jiménez A., Jordá E.G., Pallás M., Rimbau V., Sureda F.X., Verdaguer E.Fuentes:scopusInhibition of the cdk5/MEF2 pathway is involved in the antiapoptotic properties of calpain inhibitors in cerebellar neurons
ArticleAbstract: Experimental data implicate calpain activation in the pathways involved in neuronal apoptosis. IndeePalabras claves:apoptosis, Calpain, Cdk5/p25, MEF2Autores:Alvira D., Antoni Camins, Jiménez A., Pallás M., Rimbau V., Verdaguer E.Fuentes:scopusKainic acid-induced neuronal cell death in cerebellar granule cells is not prevented by caspase inhibitors
ArticleAbstract: 1. We examined the role of non-NMDA receptors in kainic acid (KA)-induced apoptosis in cultures of rPalabras claves:Ac-DEVD-CHO, apoptosis, Calpain, Caspases, Cerebellar granule cells, colchicine, glutamate, Kainic acid, Par-4, Z-VAD.fmkAutores:Antoni Camins, Camarasa J., Canudas A.M., Escubedo E., García-Jordà E., Jiménez A., Pallás M., Stranges A., Sureda F.X., Verdaguer E.Fuentes:scopus