Mostrando 10 resultados de: 32
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scopus(32)
Flavopiridol: An antitumor drug with potential application in the treatment of neurodegenerative diseases
ArticleAbstract: Several lines of evidence show that cyclin-dependent kinases (CDKs) contribute to neurodegenerativePalabras claves:Autores:Antoni Camins, Canudas A.M., Jiménez A., Jordá E.G., Pallás M., Verdaguer E.Fuentes:scopusEvaluation of neuronal cell death by laser scanning cytometry
ArticleAbstract: We developed a method in which laser scanning cytometry (LSC) is applied to evaluate cell viability.Palabras claves:Autores:Antoni Camins, Camarasa J., Escubedo E., Jiménez A., Pallás M., Pubill D., Rimbau V., Verdaguer E.Fuentes:scopusEvaluation of potential pro-survival pathways regulated by melatonin in a murine senescence model
ArticleAbstract: We examined the effect of melatonin on pro-survival processes in three groups of mice. Untreated senPalabras claves:aging, Amyloid β, BRAIN, Cysteine proteases, Sirt1Autores:Antoni Camins, Coto-Montes A., Gutiérrez-Cuesta J., Jiménez A., Pallás M., Tajes M.Fuentes:scopusEvaluation of the neuronal apoptotic pathways involved in cytoskeletal disruption-induced apoptosis
ArticleAbstract: The cytoskeleton is critical to neuronal functioning and survival. Cytoskeletal alterations are invoPalabras claves:calcium, Calpainsl, Caspases, Cytoskeleton, Serine-proteasesAutores:Allgaier C., Antoni Camins, Arriba S.G.D., Jiménez A., Jordá E.G., Pallás M., Verdaguer E.Fuentes:scopusEvidence in favour of a role for peripheral-type benzodiazepine receptor ligands in amplification of neuronal apoptosis
ArticleAbstract: The mitochondrial peripheral benzodiazepine receptor (PBR) is involved in a functional structure desPalabras claves:AIF, Cerebellar granule cells, colchicine, Cyt c, Mitochondrial permeability transition, Peripheral benzodiazepine receptorAutores:Antoni Camins, Canudas A.M., Folch J., Jiménez A., Jordá E.G., Pallás M., Sureda F.X., Verdaguer E.Fuentes:scopusFurther characterization of an adenosine transport system in the mitochondrial fraction of rat testis
ArticleAbstract: Previous work from our laboratory has demonstrated the presence of high- affinity binding sites forPalabras claves:Adenosine uptake, Benzodiazepine receptor ligand, mitochondrial, Mitochondrion, Testis, rat, [ H]Adenosine 3Autores:Antoni Camins, Camarasa J., Escubedo E., Jiménez A., Lladó S., Pallás M., Pubill D.Fuentes:scopusGSK-3β inhibition and prevention of mitochondrial apoptosis inducing factor release are not involved in the antioxidant properties of SB-415286
ArticleAbstract: The antioxidant effects of lithium and SB-415286, two glycogen synthase kinase-3β (GSK-3β) inhibitorPalabras claves:AIF, apoptosis, GSK-3β, Lithium, Oxidative Stress, SB-415286Autores:Antoni Camins, Folch J., Jiménez A., Pallás M., Rimbau V., Yeste-Velasco M.Fuentes:scopusC-phycocyanin protects cerebellar granule cells from low potassium/serum deprivation-induced apoptosis
ArticleAbstract: We tested the potential cytoprotective role of C-phycocyanin in rat cerebellar granule cell culturesPalabras claves:apoptosis, C-Phycocyanin, cell cycle, Cerebellar granule cells, Flow cytometry, Laser scanning cytometry, Oxidative Stress, RATAutores:Antoni Camins, Camarasa J., Escubedo E., González R., Jiménez A., Pallás M., Pubill D., Rimbau V., Romay C., Sureda F.X.Fuentes:scopusEffects of melatonin in the brain of the senescence-accelerated mice-prone 8 (SAMP8) model
ArticleAbstract: Summary. Senescence-accelerated mice (SAM) represent an aging model establish by selective inbreedinPalabras claves:CDK5, GSK3beta, melatonin, TauAutores:Antoni Camins, Gutiérrez-Cuesta J., Jiménez A., Pallás M., Tajes M.Fuentes:scopusCyclosporin A enhances colchicine-induced apoptosis in rat cerebellar granule neurons
ArticleAbstract: 1 Cyclosporin A (CsA, 1-50 μM), an immunosuppressive drug with known neurotoxic effects, did not decPalabras claves:CDK5, colchicine, Cyclosporin A, flavopiridol, Neurotoxicity, RoscovitineAutores:Antoni Camins, Canudas A.M., Jiménez A., Jordá E.G., Pallás M., Rimbau V., Sureda F.X., Verdaguer E.Fuentes:scopus