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scopus(12)
Acute Vhl gene inactivation induces cardiac HIF-Dependent erythropoietin gene expression
ArticleAbstract: Von Hippel Lindau (Vhl) gene inactivation results in embryonic lethality. The consequences of its inPalabras claves:Autores:Albacete-Albacete L., Aragonés J., Balsa E., Elorza A., Fernández-Criado C., Fuertes E., Manuel Ortiz de Landázuri, Miró-Murillo M., Ordóñez A., Soro-Arnáiz I., Vara-Vega A., Vazquez S.N.Fuentes:scopusEvidence for the Involvement of Diacylglycerol Kinase in the Activation of Hypoxia-inducible Transcription Factor 1 by Low Oxygen Tension
ArticleAbstract: Hypoxia-inducible factor 1 (HIF-1) induces a gene expression program essential for the cellular adapPalabras claves:Autores:Alfranca A., Aragonés J., Jones D.R., Manuel Ortiz de Landázuri, Martin-Puig S., Mérida I., San Juan M.A., Vara A., Vidal F.Fuentes:scopusDithiocarbamates trigger differentiation and induction of CD11c gene through AP-1 in the myeloid lineage
ArticleAbstract: It has recently been shown that the alteration of the cell-redox status affects the transcription faPalabras claves:Autores:Aragonés J., Corbí A.L., Del Arco P.G., López-Cabrera M., López-Rodríguez C., Manuel Ortiz de Landázuri, Redondo J.M.Fuentes:scopusMyeloid hypoxia-lnducible factors in inflammatory diseases
ArticleAbstract: Hypoxia inducible factors (HIFI and HIF2) have emerged as central regulators of the activity of myelPalabras claves:Hypoxia, Hypoxia-inducible factor (HIF), inflammation, MacrophagesAutores:Acosta-Lborra B., Aragonés J., Elorza A., Manuel Ortiz de LandázuriFuentes:scopusLack of evidence for the involvement of the phosphoinositide 3-kinase/Akt pathway in the activation of hypoxia-inducible factors by low oxygen tension
ArticleAbstract: Hypoxia-inducible factors (HIF) belong to an evolutionary conserved family of transcription factors,Palabras claves:Autores:Alfranca A., Álvarez-Tejado M., Aragonés J., Manuel Ortiz de Landázuri, Peso L.D., Vara A.Fuentes:scopusHIF2α Acts as an mTORC1 Activator through the Amino Acid Carrier SLC7A5
ArticleAbstract: The mammalian target of rapamycin (mTOR) pathway, which is essential for cell proliferation, is reprPalabras claves:Autores:Acosta-Iborra B., Albacete-Albacete L., Aragonés J., de Cárcer G., Elorza A., Giménez-Bachs J.M., Malumbres M., Manuel Ortiz de Landázuri, Marsboom G., Martín del Río R., Meléndez-Rodríguez F., Ordóñez A., Rodríguez-Vaello V., Salinas A., Sánchez-Prieto R., Sánchez‐Madrid F., Serrano-Oviedo L., Soro-Arnáiz I., Vara-Vega A.Fuentes:scopusMacrophage oxygen sensing modulates antigen presentation and phagocytic functions involving IFN-γ production through the HIF-1α transcription factor
ArticleAbstract: Low oxygen tension areas are found in inflamed or diseased tissues where hypoxic cells induce survivPalabras claves:Autores:Acosta-Iborra B., Aragonés J., Calzada M.J., Elorza A., Manuel Ortiz de Landázuri, Martín-Cofreces N.B., Martin-Puig S., Miro M., Olazabal I.M., Sánchez‐Madrid F.Fuentes:scopusMitochondrial reprogramming through cardiac oxygen sensors in ischaemic heart disease
ReviewAbstract: Under hypoxic conditions, mitochondria can represent a threat to the cell because of their capacityPalabras claves:Hypoxia-inducible factor, Ischaemia, Mitochondria, preconditioning, Prolyl hydroxylaseAutores:Aragonés J., Cadenas S., Manuel Ortiz de LandázuriFuentes:scopusUp-regulation of vascular endothelial growth factor receptor Flt-1 after endothelial denudation: Role of transcription factor Egr-1
ArticleAbstract: Vascular endothelial growth factor (VEGF) is highly expressed in vascular remodeling processes and aPalabras claves:Autores:Alfranca A., Aragonés J., Manuel Ortiz de Landázuri, Vidal F.Fuentes:scopusReduced intracellular oxidative metabolism promotes firm adhesion of human polymorphonuclear leukocytes to vascular endothelium under flow conditions
ArticleAbstract: The interaction of polymorphonuclear leukocytes (PMN) with the vascular endothelium and their subseqPalabras claves:adhesion, antioxidant, flow, Hypoxia, NeutrophilAutores:Aragonés J., Del Pozo M.A., Luscinskas F.W., Manuel Ortiz de Landázuri, Montoya M.C.Fuentes:scopus