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scopus(6)
(±)-huprine Y, (-)-huperzine A and tacrine do not show neuroprotective properties in an apoptotic model of neuronal cytoskeletal alteration
ArticleAbstract: Acetylcholinesterase inhibitors (AChEI) are among the drugs most widely used in the treatment of AlzPalabras claves:acetylcholinesterase inhibitors, Cerebellar granule cells, colchicine, neuronal death, RATAutores:Antoni Camins, Camps P., Canudas A.M., Jiménez A., Jordá E.G., Muñoz-Torrero D., Pallás M., Rimbau V., Verdaguer E.Fuentes:scopusNeuroprotective effects of (±)-huprine Y on in vitro and in vivo models of excitoxicity damage
ArticleAbstract: We have investigated the neuroprotective effects of (±)-huprine Y on excitotoxic lesions in rat cerePalabras claves:3-nitropropionic acid, Cerebellar granule cells, glutamate, Huprines, neuroprotectionAutores:Antoni Camins, Camps P., Canudas A.M., Jiménez A., Muñoz-Torrero D., Pallás M., Pubill D., Sureda F.X., Verdaguer E.Fuentes:scopusNew oxapolycyclic cage amines with NMDA receptor antagonist and trypanocidal activities
ArticleAbstract: The synthesis of several (1,2,3,5,6,7-hexahydro-1,5:3,7-dimethano-4-benzoxonin-3-yl)amines and relatPalabras claves:Amantadine, Indantadol, Memantine, NGP1-01, NMDA, Polycyclic cage compounds, TrypanosomaAutores:Antoni Camins, Camps P., Duque M.D., Kelly J.M., López-Querol M., Prathalingam S.R., Sureda F.X., Torres E., Valverde E., Vázquez S.Fuentes:scopusNovel donepezil-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation
ArticleAbstract: A novel series of donepezil-tacrine hybrids designed to simultaneously interact with the active, perPalabras claves:Autores:Andrisano V., Antoni Camins, Badia A., Bartolini M., Bidon-Chanal A., Camps P., Clos M.V., Estelrich J., Formosa X., Galdeano C., Gómez T., Lizondo M., Luque F.J., Mancini F., Muñoz-Torrero D., Pallás M., Scarpellini M., Viayna E.Fuentes:scopusNovel huprine derivatives with inhibitory activity toward β-amyloid aggregation and formation as disease-modifying anti-Alzheimer drug candidates
ArticleAbstract: A new family of dual binding site acetylcholinesterase (AChE) inhibitors has been designed, synthesiPalabras claves:Acetylcholinesterase, drug design, Inhibitors, β-amyloid peptides, β-secretaseAutores:Andrisano V., Antoni Camins, Arce M.P., Badia A., Bartolini M., Bidon-Chanal A., Camps P., Clos M.V., Galdeano C., Gómez T., Junyent F., Luque F.J., Mancini F., Muñoz-Torrero D., Pallás M., Ramírez L., Ratia M., Rodríguez-Franco M.I., Verdaguer E., Viayna E.Fuentes:scopusSynthesis and pharmacological evaluation of several ring-contracted amantadine analogs
ArticleAbstract: The synthesis of several (3-noradamantyl)amines, [(3-noradamantyl)methyl]amines, (3,7-dimethyl-1-bisPalabras claves:Amantadine, influenza, Memantine, NMDA receptor antagonist, Polycyclic cage compounds, TrypanosomiasisAutores:Antoni Camins, Camps P., Cortés D., De Clercq E., Duque M.D., Ivorra D., Kelly J.M., López-Querol M., Naesens L., Pallás M., Prathalingam S.R., Romero V., Sureda F.X., Vázquez S.Fuentes:scopus