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Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology(1)
Current Issues in Molecular Biology(1)
Current Medicinal Chemistry(1)
Drug Development Research(1)
Elsevier B.V.(1)
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Farmacología y terapéutica(7)
Bioquímica(4)
Enfermedades(4)
Microorganismos, hongos y algas(4)
Fisiología y materias afines(1)
Traditional and Computational Screening of Non-Toxic Peptides and Approaches to Improving Selectivity
ReviewAbstract: Peptides have positively impacted the pharmaceutical industry as drugs, biomarkers, or diagnostic toPalabras claves:hemolysis, IN SILICO, Machine Learning, Peptides, toxicityAutores:Alberto A. Robles-Loaiza, Bruno Mendes, Carolina Proaño-Bolaños, Edgar A. Pinos-Tamayo, Gomes P.A.D.C., Jose Rafael de Almeida, Josselyn A. Ortega-Pila, Plisson F., Teixeira C.A.S.Fuentes:googleorcidscopusSnake Venom Peptides and Low Mass Proteins: Molecular Tools and Therapeutic Agents
ArticleAbstract: Snake venoms are natural sources of biologically active molecules that are able to act selectively aPalabras claves:Bradykinin-potentiating peptide, Crotamine, Disintegrin, Natriuretic peptide, Sarafotoxin, Three-finger toxinAutores:Caldeira C.A.S., Carregari V.C., Coutinho-Neto A., de Azevedo Calderon L., Gomes P.A.D.C., Huancahuire-Vega S., Jose Rafael de Almeida, Marangoni S., R. K. Watanabe, Resende L.M., Saulo L. Silva, Soares A.M., Valed N.Fuentes:googleorcidscopusHarnessing snake venom phospholipases A2 to novel approaches for overcoming antibiotic resistance
ArticleAbstract: The emergence of antibiotic resistance drives an essential race against time to reveal new molecularPalabras claves:antibacterial peptides, antibiotic-resistant bacteria, Peptidomimetics, Phospholipase A 2, Snake venomAutores:Antonio L.V. Palacios, Bruno Mendes, Gomes P.A.D.C., Jose Rafael de Almeida, Ricardo S.P. Patiño, Saulo L. Silva, Teixeira C.A.S.Fuentes:googleorcidscopusA novel synthetic peptide inspired on Lys49 phospholipase A2 from Crotalus oreganus abyssus snake venom active against multidrug-resistant clinical isolates
ArticleAbstract: Currently, the evolving and complex mechanisms of bacterial resistance to conventional antibiotics aPalabras claves:Antibacterial activity, Biomimetic peptide, Phospholipase A 2, Phospholipase A2, Snake venomAutores:Bruno Mendes, Fernandes P.A., Gomes P.A.D.C., Jose Rafael de Almeida, Lancellotti M., Marangoni S., Passos Ó., Ramos M.J., Saulo L. Silva, Vale N.Fuentes:googleorcidscopusPeptides to Tackle Leishmaniasis: Current Status and Future Directions
ArticleAbstract: Peptide-based drugs are an attractive class of therapeutic agents, recently recognized by the pharmaPalabras claves:Amastigote, Drug Discovery, Leishmania spp, Peptides, PromastigoteAutores:Alberto A. Robles-Loaiza, Alejandro Pinos-Tamayo, Alves C., Bruno Mendes, Edgar A. Pinos-Tamayo, Gomes P.A.D.C., Jose Rafael de Almeida, Teixeira C.A.S.Fuentes:googleorcidscopusLessons from a Single Amino Acid Substitution: Anticancer and Antibacterial Properties of Two Phospholipase A2-Derived Peptides
ArticleAbstract: The membrane-active nature of phospholipase A2-derived peptides makes them potential candidates forPalabras claves:Agkistrodon, leucine, Membrane, Phenylalanine, Venom peptidesAutores:Alves C., Bruno Mendes, Fernandes P.A., Franchi G.C., Gomes P.A.D.C., Jose Rafael de Almeida, Lancellotti M., Passos Ó., Ramos M.J., Saulo L. Silva, Vale N.Fuentes:googleorcidscopusUnlocking the potential of snake venom-based molecules against the malaria, Chagas disease, and leishmaniasis triad
ArticleAbstract: Malaria, leishmaniasis and Chagas disease are vector-borne protozoal infections with a disproportionPalabras claves:Peptides, Snake venoms, Vector-borne protozoan infectionsAutores:Ana Gomes, Bruno Mendes, David Salazar-Valenzuela, Denise Duarte, Fátima Nogueira, Gomes P.A.D.C., Jose Rafael de Almeida, Luísa Aguiar, Mariana Borges Costa Brioschi, Mariana Ferreira, Miguel D.C., Paula Gameiro, Sofia Cortes, Teixeira C.A.S.Fuentes:googleorcidscopusPotential use of 13-mer peptides based on phospholipase and oligoarginine as leishmanicidal agents
ArticleAbstract: Phospholipase A<inf>2</inf> toxins present in snake venoms interact with biological membranes and sePalabras claves:Leishmanicidal activity, Oligoarginine, peptide, PhospholipaseAutores:Bruno Mendes, Gadelha F.R., Gomes P.A.D.C., Jose Rafael de Almeida, Miguel D.C., Saulo L. Silva, Vale N.Fuentes:googleorcidscopus