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Diethylphosphoryl-oxymab (DEPO-B) as a solid coupling reagent for amide bond formation
ArticleAbstract: A new phosphonium based coupling reagent DEPO-B has been synthesized from 5-(hydroxyimino)-1,3-dimetPalabras claves:coupling reagent, Diethylphosphoryl-OxymaB, Hydrolytic stability, Phosphonium salts, SOLUBILITYAutores:Alberício F., B. G. De la Torre, El-Faham A., Jad Y.E., Kumar A.Fuentes:scopusFormation of N <sup>α</sup>-terminal 2-dialkyl amino oxazoles from guanidinated derivatives under mild conditions
ArticleAbstract: Oxazole-containing peptides are an important class of molecules in medicinal chemistry programs. HerPalabras claves:Autores:Alberício F., B. G. De la Torre, El-Faham A., Kumar A., Mhlongo J.T., Monaim S.A.H.A.Fuentes:scopusExploiting azido-dichloro-triazine as a linker for regioselective incorporation of peptides through their N, O, S functional groups
ArticleAbstract: In the field of bioconjugation, linker development has witnessed massive growth in recent years. 2,4Palabras claves:Bioconjuation, Linker, Orthogonal chemoselectivity, Orthogonality, Solid-phase peptide synthesisAutores:Alberício F., B. G. De la Torre, El-Faham A., Kumar A., Sharma A.Fuentes:scopusN-methylation in amino acids and peptides: Scope and limitations
ReviewAbstract: Active pharmaceutical ingbkp_redients (APIs) can be divided into two types, namely chemical and biolPalabras claves:cyclic peptides, NMAA, side-reactions, Solid-phase peptide synthesisAutores:Alberício F., B. G. De la Torre, El-Faham A., Jad Y.E., Kumar A., Monaim S.A.H.A., Sharma A.Fuentes:scopusIn situ Fmoc removal - a sustainable solid-phase peptide synthesis approach
ArticleAbstract: Solid-phase peptide synthesis (SPPS) is the strategy of choice for the synthesis of peptides for resPalabras claves:Autores:Alberício F., B. G. De la Torre, Kumar A., Sharma A.Fuentes:scopusMicrowave-Assisted Green Solid-Phase Peptide Synthesis Using γ-Valerolactone (GVL) as Solvent
ArticleAbstract: The increasing demand for synthetic peptides in various research fields raises a challenge, namely,Palabras claves:Automatic synthesis, Green solvent, peptide, Sustainable chemistryAutores:Alberício F., B. G. De la Torre, Collins J.M., Jad Y.E., Kumar A.Fuentes:scopusLiquid-Phase Peptide Synthesis (LPPS): A Third Wave for the Preparation of Peptides
ReviewAbstract: Since the last century, peptides have gained wide acceptance as drugs, with almost 100 already in thPalabras claves:Autores:Alberício F., B. G. De la Torre, Kumar A., Sharma A.Fuentes:scopusInvestigating green ethers for the precipitation of peptides after global deprotection in solid-phase peptide synthesis
ReviewAbstract: Diethyl ether and methyl tert-butyl ether are the solvents most widely used for peptide precipitatioPalabras claves:Autores:Al Musaimi O., Alberício F., B. G. De la Torre, Basso A., Collins J.M., Jad Y.E., Kumar A.Fuentes:scopusTroubleshooting When Using γ-Valerolactone (GVL) in Green Solid-Phase Peptide Synthesis
ArticleAbstract: The synthesis of peptides for both research and API production is conveniently carried out using thePalabras claves:difficult peptides, Green solvent, microwave assisted synthesis, side reactionsAutores:Alberício F., B. G. De la Torre, Collins J.M., Kumar A., Nandhini K.P., Thompson-Adewumi A.Fuentes:scopusScope and limitations of γ-valerolactone (GVL) as a green solvent to be used with base for FMOC removal in solid phase peptide synthesis
ArticleAbstract: GVL is a green solvent used in Fmoc-based solid-phase peptide synthesis. It is susceptible to ring oPalabras claves:4-methylpiperidine, Acyl piperidide, DFT, IR, NMR, PiperidineAutores:Alberício F., B. G. De la Torre, Kumar A., Sharma A.Fuentes:scopus