Bisphosphonate-related osteonecrosis of the jaw


Abstract:

Bisphosphonates (BPs) have been used for the management of bone metabolic diseases. Currently their therapeutic use has increased, as also have their adverse effects, one of the most important being the bisphosphonate-related osteonecrosis of the jaw (BRONJ), a complication of difficult treatment and solution. Until now, the physiopathology of BRONJ remains unclear, and its treatment is uncertain. Although the literature provides several treatment options, there is no defined protocol. We present a review about BRONJ, focusing on its pathogenesis and its reported forms of treatment. © 2012 Elsevier Editora Ltda. All rights reserved.

Año de publicación:

2012

Keywords:

  • Jaw
  • Alendronate
  • Osteonecrosis

Fuente:

scopusscopus

Tipo de documento:

Review

Estado:

Acceso restringido

Áreas de conocimiento:

    Áreas temáticas:

    • Enfermedades
    • Cirugía y especialidades médicas afines