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"Getting from here to there"-mechanisms and limitations to the activation of the androgen receptor in castration-resistant prostate cancer
ReviewAbstract: Despite the clinical regression that typifies the initial response of advanced prostate cancer to goPalabras claves:androgen receptor, Androgens, Steroid metabolismAutores:McPhaul M., Richard J. Auchus, Sharifi N.Fuentes:scopus11-Ketotestosterone Is the Dominant Circulating Bioactive Androgen during Normal and Premature Adrenarche
ArticleAbstract: Context: Adrenarche refers to the rise of dehydroepiandrosterone sulfate (DHEA-S) associated with thPalabras claves:Autores:Auchus G.C., Kasa-Vubu J.Z., Lerario A.M., Rainey W.E., Rege J., Richard J. Auchus, Smith J.M., Turcu A.F., White P.C.Fuentes:scopus11-Oxygenated Androgens Useful in the Setting of Discrepant Conventional Biomarkers in 21-Hydroxylase Deficiency
ArticleAbstract: Context: Serum 17-hydroxyprogesterone (17OHP) and androstenedione (A4) are the conventional biomarkePalabras claves:alternate androgens, androgen excess, Biomarkers, Congenital adrenal hyperplasia, monitoring therapy, steroidogenesisAutores:Brookner B., Jha S., Merke D.P., Richard J. Auchus, Sinaii N., Turcu A.F.Fuentes:scopus11-Oxygenated C19 Steroids Do Not Distinguish the Hyperandrogenic Phenotype of PCOS Daughters from Girls with Obesity
ArticleAbstract: Context: Hyperandrogenemia (HA) is a consistent reproductive phenotype in women with polycystic ovarPalabras claves:11-oxygenated C19 androgens, Hyperandrogenemia, obesity, Polycystic ovary syndromeAutores:Dunaif A., Legro R.S., Richard J. Auchus, Sisk R., Torchen L.C., Turcu A.F.Fuentes:scopus11-Oxygenated C<inf>19</inf> Steroids Do Not Decline with Age in Women
ArticleAbstract: The ovaries and adrenals are sources of androgens in women. Although dehydroepiandrosterone (DHEA),Palabras claves:Autores:Nanba A.T., Rainey W.E., Rege J., Ren J., Richard J. Auchus, Turcu A.F.Fuentes:scopus11-Oxygenated androgens are biomarkers of adrenal volume and testicular adrenal rest tumors in 21-hydroxylase deficiency
ArticleAbstract: Context: Patients with 21-hydroxylase deficiency (21OHD) have long-term complications, resulting froPalabras claves:Autores:Avila N.A., Elman M.S., Mallappa A., Marko J., Merke D.P., Rao H., Richard J. Auchus, Tsodikov A., Turcu A.F.Fuentes:scopus11-Oxygenated androgens in health and disease
ReviewAbstract: The adrenal gland is a source of sex steroid precursors, and its activity is particularly relevant dPalabras claves:Autores:Rainey W.E., Rege J., Richard J. Auchus, Turcu A.F.Fuentes:scopus24-Hour Profiles of 11-Oxygenated C<inf>19</inf> Steroids and Δ<sup>5</sup>-Steroid Sulfates during Oral and Continuous Subcutaneous Glucocorticoids in 21-Hydroxylase Deficiency
ArticleAbstract: Background: Optimal management of androgen excess in 21-hydroxylase deficiency (21OHD) remains challPalabras claves:11-oxyandrogens, 21-hydroxylase deficiency, CAH, Circadian hormones, Congenital adrenal hyperplasia, cortisol 24-hour profileAutores:Byrd J.B., Chen X., Mallappa A., Merke D.P., Nanba A.T., Nella A.A., Richard J. Auchus, Turcu A.F., Zhao L.Fuentes:scopus5α-androstane-3α,17β-diol is formed in tammar wallaby pouch young testes by a pathway involving 5α-pregnane-3α,17α-diol-20-one as a key intermediate
ArticleAbstract: The synthetic pathway by which 5α-androstane-3α,17β-diol (5α-adiol) is formed in the testes of tammaPalabras claves:Autores:Estabrook R.W., Guryev O.L., Leihy M.W., Osborn S.M., Renfree M.B., Richard J. Auchus, Shaw G., Wilson J.D.Fuentes:scopus70. Determination of satisfaction with the use of the subdermal etonogestrel implant “Implanon” as a contraception method, its side effects and reasons for discontinuing the …
OtherAbstract: Purpose In Ecuador, teen pregnancy is a major public health concern with a rate of 81 per 1000. ForPalabras claves:Autores:Pablo EndaraFuentes:google