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1,3,5-Triazino Peptide Derivatives: Synthesis, Characterization, and Preliminary Antileishmanial Activity
ArticleAbstract: A library of short di-, tri-, and tetra-peptides with an s-triazine moiety at the N terminus and eitPalabras claves:1,3,5-triazine derivatives, antileishmanial compounds, morpholines, Peptides, piperidinesAutores:Abd El-Rahman M.M., Alberício F., B. G. De la Torre, Bekhit A.A., El-Faham A., Khalil H.H., Khattab S.N.Fuentes:scopus2018 FDA Tides Harvest
ReviewAbstract: In 2018, the United States Food and Drug Administration (FDA) approved a total of 59 new drugs, threPalabras claves:Dotatate, drugs, Inotersen, Lutathera, Oligonucleotides, Onpattro, Patisiran, Peptides, Pharmaceutical market, TegsediAutores:Al Musaimi O., Al Shaer D.M., Alberício F., B. G. De la TorreFuentes:scopus2022 FDA TIDES (Peptides and Oligonucleotides) Harvest
ArticleAbstract: A total of 37 new drug entities were approved in 2022; although that year registered the lowest numbPalabras claves:drugs, FDA, gadopiclenol, lutetium ( Lu) vipivotide tetraxetan 177, lutetium (177Lu) vipivotide tetraxetan, Oligonucleotides, Peptides, terlipressin, tirzepatide, vutrisiranAutores:Al Musaimi O., Al Shaer D.M., Alberício F., B. G. De la TorreFuentes:scopusThe potential of N-alkoxymethyl groups as peptide backbone protectants
ArticleAbstract: In this study, the potential of N-alkoxymethyl groups as protectants for the peptide backbone has bePalabras claves:Backbone N-alkylation, Backbone protecting groups, N-Alkoxymethyl, Peptides, SPPSAutores:Alberício F., Fernandez-Llamazares A.I., Jan SpenglerFuentes:googlescopusSynthesis of New Peptide-Based Ligands with 1,2-HOPO Pendant Chelators and Thermodynamic Evaluation of Their Iron(III) Complexes**
ArticleAbstract: Hydroxypyridones (HOPOs) are an important class of chelating compounds. They bind strongly to hard mPalabras claves:Chelation, constants, Peptides, Protonation constants, Siderophore, stabilityAutores:Al Shaer D.M., Alberício F., B. G. De la TorreFuentes:scopusThe Pharmaceutical Industry in 2022: An Analysis of FDA Drug Approvals from the Perspective of Molecules
ReviewAbstract: While 2021 ended with the world engulfed in the COVID-19 Omicron wave, 2022 has ended in almost allPalabras claves:Antibodies, biologics, chemical entities, fluorine-based drugs, imaging, Natural products, new chemical entities, Oligonucleotides, Peptides, TIDESAutores:Alberício F., B. G. De la TorreFuentes:scopusBacteria Hunt Bacteria through an Intriguing Cyclic Peptide
ReviewAbstract: In the last few decades, peptides have been victorious over small molecules as therapeutics due to tPalabras claves:Antibiotics, biological activity, cyclic antimicrobial peptides, Drug Discovery, PeptidesAutores:Alberício F., B. G. De la Torre, El-Faham A., Monaim S.A.H.A., Somboro A.M.Fuentes:scopusCyclic amino acid linkers stabilizing key loops of brain derived neurotrophic factor
ArticleAbstract: Based on β-turn-like BDNF loops 2 and 4, involved in receptor interaction, cyclic peptide replicas wPalabras claves:BDNF, Growth factors, Peptides, Secondary peptide structure mimetics, β-TurnAutores:Almeida R.D., Andreu D., B. G. De la Torre, Baeza J.L., Garcı́a-López M.T., Gerona-Navarro G., Gonzalez-Muniz R., Jaffrey S.R., Jiménez M.A., Martín-Martínez M., Santiveri C.M.Fuentes:scopusCell Penetrating Peptides as potential drug carriers
ReviewAbstract: The discovery and development of natural, synthetic or peptidomimetic cell-penetrating peptides (CPPPalabras claves:Blood-brain barrie, cell-penetrating peptides, Molecular transportes, PeptidesAutores:Alberício F., Hortensia Rodriguez Cabrera, Pulido X.C., Royo M.Fuentes:scopusDisplay technology on filamentous phage in the searchfor anti-infective biological agents
ReviewAbstract: Introduction: The causes of antibiotic resistance are complex. The phage display technology has beenPalabras claves:Antibodies, Bacteriophages, Biopaning, Combinatorial libraries, Infectious diseases, Peptides, Phage display technologyAutores:Antúnez M.P., Camacho F., Ramos O.S., Santiago Nelson Vispo, Toledo R.Fuentes:scopus