Mostrando 10 resultados de: 13
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Article(13)
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Biotecnologia Aplicada(3)
Journal of Pharmaceutical and Biomedical Analysis(2)
Tetrahedron Letters(2)
Arzneimittel-Forschung/Drug Research(1)
Bioconjugate Chemistry(1)
Bio-analytical method based on MALDI-MS analysis for the quantification of CIGB-300 anti-tumor peptide in human plasma
ArticleAbstract: A fully validated bio-analytical method based on Matrix-Assisted-Laser-Desorption/Ionization-Time ofPalabras claves:Anti-tumor peptide, Bio-analytical method, Full validation, Human plasma, Maldi-tofAutores:Audain E., B. G. De la Torre, Besada-Pérez V., Cabrales-Rico A., Garay H.E., Gómez J.A., González L.J., Machado Y.J., Marcelo J.L., Morales O., Perea-Rodríguez S.E., Perera Y., Reyes O., Reyes V.Fuentes:scopusAntitumor effect of a novel proapoptotic peptide that impairs the phosphorylation by the protein kinase 2 (casein kinase 2)
ArticleAbstract: Protein Kinase (casein kinase 2, CK2) is a serine-threonine kinase that is frequently dysregulated iPalabras claves:Autores:Acevedo B.E., Alonso D.F., Falcón-Cama V., López-Mola E., Mendoza O., Perea-Rodríguez S.E., Puchades Y., Reyes O., Santiago Nelson Vispo, Santos-Savio A., Silva R., Torrens I.Fuentes:scopusDevelopment and validation of a bioanalytical LC-MS method for the quantification of GHRP-6 in human plasma
ArticleAbstract: Growth hormone-releasing peptide 6 (GHRP-6, His-(DTrp)-Ala-Trp-(DPhe)-Lys-NH 2, MW=872.44Da) is a poPalabras claves:GHRP-6, internal standard, LC-MS, Method validation, PlasmaAutores:Besada-Pérez V., Betancourt L., Cabrales A., García G., Gil J., González L.J., Moya G., Padrón G., Reyes O., Sánchez A., Vivian Morera CórdovaFuentes:scopusCIGB-300, a novel proapoptotic peptide that impairs the CK2 phosphorylation and exhibits anticancer properties both in vitro and in vivo
ArticleAbstract: Protein Kinase CK2 is a serine-threonine kinase frequently deregulated in many human tumors. Here, wPalabras claves:apoptosis, Cancer targeted therapy, Casein kinase 2Autores:Acevedo B.E., Alonso D.F., Ariosa J., Bacardí D.M., Baladron I., Besada-Pérez V., Betancourt L., Castellanos L.R., Cosme K., Cruz M., Díaz A., Falcón-Cama V., Farina H., Garay H.E., Gil J., Gómez D., Gómez R., González L.J., Hernández I., Herrera L., López C., López-Mola E., López-Saura P.A., Marcelo J.L., Mendoza O., Perea-Rodríguez S.E., Perera Y., Puchades Y., Reyes O., Rodriguez A., Sánchez A., Santana A., Serrano J.M., Sigman H., Silva R., Solares M., Thelvia I. Ramos Gómez, Valenzuela-Silva C.M.Fuentes:googlescopusIdentification and characterization of phage-displayed peptide mimetics of Neisseria meningitidis serogroup B capsular polysaccharide
ArticleAbstract: Neisseria meningitidis causes meningitis and septicemia. There is no single vaccine against all seroPalabras claves:Capsular polysaccharides, Meningococcal vaccines, Neisseria meningitidis, Polysaccharide mimeticsAutores:Batista Y., Carmenate T., Chinea G., Cobas K., Coizeau E., Cruz-Leal Y., Garay H.E., Guillén-Nieto G.E., Menéndez T., Reyes O., Santiago Nelson VispoFuentes:scopusIdentification of the first antagonist peptide that inhibits biological effects of interleukin-15
ArticleAbstract: Interleukin-15 (IL-15) is a pro-inflammatory cytokine that is expressed in several autoimmune and inPalabras claves:Alpha receptor, antagonist, Cytokine, IL-15, peptideAutores:Alexey Llópiz-Arzuaga, Altruda F., Ancisar J.A., Arrieta C.A., Cabrales A., Chico A., Estévez M., Garay H.E., Geronimo H., Guillén-Nieto G.E., Machado A.C., Noda J., Ojeda M., Perea-Rodríguez S.E., Reyes O., Rodríguez-Álvarez Y., Sánchez A., Santos-Savio A., Silengo L., Suaréz J., Vázquez M.Fuentes:googlescopusUnconventional synthesis of nitrogenated heterocycles with potencial bioactive properties
ArticleAbstract:Palabras claves:Autores:Hortensia Rodriguez Cabrera, Martín O., Ochoa E., Reyes O., Suárez Navarro M.Fuentes:googlescopusProtective immune response against Neisseria meningitidis serogroup B after immunization with peptides mimicking a capsular polysaccharide epitope
ArticleAbstract:Palabras claves:Autores:Brown E., Caballero E., Carmenate T., Chinea G., Cobas K., Coizeau E., Cruz Y., Garay H.E., González S., Guillén-Nieto G.E., Martín A., Menéndez T., Noda J., Reyes O., Santiago Nelson Vispo, Soria Y., Vivian Morera Córdova, Yero D.Fuentes:scopusSolid phase synthesis of 3-(5'-carboxypentyl)-5-substituted tetrahydro- 2H-1,3,5-thiadiazin-2-thione derivatives
ArticleAbstract: The solid phase synthesis of 3-(5'-carboxypentyl)-5-substituted tetrahydro-2H-1,3,5-thiadiazin-2-thiPalabras claves:Resins amino acids, solid-phase synthesis, Thiadiazin-2-thionesAutores:Cruz L.J., Garay H.E., Hortensia Rodriguez Cabrera, Molero-Vilchez M.D., Ochoa C., Perez-Pineiro R., Reyes O., Suárez Navarro M.Fuentes:googlescopusSolid-phase synthesis and structural study of substituted 1,4,5,6-tetrahydro-6-oxopyridine-3-carboxylic acids
ArticleAbstract: An efficient solid-phase approach to prepare substituted 1,4,5,6-tetrahydro-6-oxopyridines bearing aPalabras claves:1,4,5,6-Tetrahydro-6-oxopyridine-3-carboxylic acids, B3LYP/6-31G* theoretical calculations, solid-phase synthesis, Wang resinAutores:Alberício F., Garay H.E., Hortensia Rodriguez Cabrera, Martín N., Martín O., Ochoa E., Reyes O., Suárez Navarro M.Fuentes:scopus