Mostrando 10 resultados de: 10
Filtros aplicados
Área temáticas
Ciencias de la computación(4)
Biología(3)
Fisiología humana(2)
Fisiología y materias afines(2)
Programación informática, programas, datos, seguridad(2)
Área de conocimiento
Bioquímica(3)
Biotecnología(3)
Proteína(2)
Biología molecular(1)
Ciencias de la computación(1)
A Novel Network Science and Similarity-Searching-Based Approach for Discovering Potential Tumor-Homing Peptides from Antimicrobials
ArticleAbstract: Peptide-based drugs are promising anticancer candidates due to their biocompatibility and low toxiciPalabras claves:Cáncer, centrality measure, chemical space network, Complex network, group fusion, in silico drug discovery, motif discovery, Similarity searching, starPep toolbox software, tumor-homing peptideAutores:Agüero-Chapin G., Aguilera-Mendoza L., Antunes A., Hortensia Rodriguez Cabrera, Martinez-Rios F.O., Maylin Romero, Yovani Marrero-PonceFuentes:googlescopusComplex Networks Analyses of Antibiofilm Peptides: An Emerging Tool for Next-Generation Antimicrobials’ Discovery
ArticleAbstract: Microbial biofilms cause several environmental and industrial issues, even affecting human health. APalabras claves:antibiofilm peptide, centrality measure, chemical space, Complex network, motif discovery, StarPep toolboxAutores:Agüero-Chapin G., Antunes A., César H. Zambrano, Ernesto Contreras-Torres, Jose R. Mora, Martinez-Rios F.O., Noel Perez, Valdés-Martiní J.R., Yovani Marrero-PonceFuentes:scopusAlignment-free methods for the detection and specificity prediction of adenylation domains
Book PartAbstract: Identifying adenylation domains (A-domains) and their substrate specificity can aid the detection ofPalabras claves:Adenylation domains, Alignment-free models, NRPS, topological indices, Transductive support vector machinesAutores:Agüero-Chapin G., Aminael Sánchez-Rodríguez, Antunes A., Pérez-Machado G., Santos M.Fuentes:googlescopusFuzzy spherical truncation-based multi-linear protein descriptors: From their definition to application in structural-related predictions
ArticleAbstract: This study introduces a set of fuzzy spherically truncated three-dimensional (3D) multi-linear descrPalabras claves:3D-protein descriptors, folding rate, fuzzy membership degree, fuzzy membership functions, MuLiMs-MCoMPAs, multi-linear algebraic forms, SCOP structural classes tensor algebra-based fuzzy spherically truncated descriptors for protein Science, spherical truncationAutores:Agüero-Chapin G., Antunes A., César R. García-Jacas, Ernesto Contreras-Torres, Julio E. Terán, Yovani Marrero-PonceFuentes:scopusExploring the Adenylation Domain Repertoire of Nonribosomal Peptide Synthetases Using an Ensemble of Sequence-Search Methods
ArticleAbstract: The introduction of two-dimension (2D) graphs and their numerical characterization for comparative aPalabras claves:Autores:Agüero-Chapin G., Aminael Sánchez-Rodríguez, Antunes A., de la Riva G.A., Maldonado E., Molina-Ruiz R., Vasconcelos V.Fuentes:googlescopusEmerging Computational Approaches for Antimicrobial Peptide Discovery
ReviewAbstract: In the last two decades many reports have addressed the application of artificial intelligence (AI)Palabras claves:Amps, Artificial Intelligence, complex networks, Evolutionary algorithms, Machine learning, Molecular descriptors, proteogenomicsAutores:Agüero-Chapin G., Antunes A., Domínguez-Pérez D., Galpert-Cañizares D., Pérez-Machado G., Teijeira M., Yovani Marrero-PonceFuentes:googlescopusTI2BioP: Topological Indices to BioPolymers. Its practical use to unravel cryptic bacteriocin-like domains
ArticleAbstract: Bacteriocins are proteinaceous toxins produced and exported by both gram-negative and gram-positivePalabras claves:Alignment methods, Artificial secondary structure, Bacteriocin, Spectral moments, topological indicesAutores:Agüero-Chapin G., Antunes A., Molina-Ruiz R., Morales-Helguera A., Pérez-Machado G., Vasconcelos V., Yunierkis Perez-CastilloFuentes:googlescopusNetwork Science and Group Fusion Similarity-Based Searching to Explore the Chemical Space of Antiparasitic Peptides
ArticleAbstract: Antimicrobial peptides (AMPs) have appeared as promising compounds to treat a wide range of diseasesPalabras claves:Autores:Agüero-Chapin G., Aguilera-Mendoza L., Ana Cristina Aguilar, Antunes A., Noel Perez, Sebastián Ayala-Ruano, Yovani Marrero-PonceFuentes:scopusNon-linear models based on simple topological indices to identify RNase III protein members
ArticleAbstract: Alignment-free classifiers are especially useful in the functional classification of protein classesPalabras claves:Alignment-free models, artificial neural networks, Clustering, Decision tree models, Spectral momentsAutores:Agüero-Chapin G., Aminael Sánchez-Rodríguez, Antunes A., de la Riva G.A., Molina-Ruiz R., Pérez-Machado G., Vasconcelos V.Fuentes:googlescopusShadowcaster: Compositional methods under the shadow of phylogenetic models to detect horizontal gene transfers in prokaryotes
ArticleAbstract: Horizontal gene transfer (HGT) plays an important role for evolutionary innovations within prokaryotPalabras claves:Horizontal gene transfer, Hybrid approach, Implicit phylogenetic model, Parametric methodAutores:Agüero-Chapin G., Aminael Sánchez-Rodríguez, Antunes A., Daniela Sánchez-Soto, Eduardo Tejera, Vinicio Danilo Armijos-Jaramillo, Yunierkis Perez-CastilloFuentes:scopus