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Organic Letters(6)
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Cleaving protected peptides from 2-chlorotrityl chloride resin. Moving away from dichloromethane
ArticleAbstract: In recent years, the work of various research groups has allowed the substitution of the hazardous sPalabras claves:Autores:Al Musaimi O., Alberício F., Alhassan M., B. G. De la Torre, Collins J.M.Fuentes:scopus2-(Dibenzylamino)butane-1,4-dithiol (DABDT), a Friendly Disulfide-Reducing Reagent Compatible with a Broad Range of Solvents
ArticleAbstract: Disulfide-reducing agents play a crucial role in bioconjugate chemistry. Herein, we describe the synPalabras claves:Autores:Alberício F., B. G. De la Torre, Mthembu S.N., Sharma A.Fuentes:scopus2-Methyltetrahydrofuran and cyclopentyl methyl ether for green solid-phase peptide synthesis
ArticleAbstract: 2-MeTHF and CPME were evaluated as greener alternatives for the most employed solvents in peptide syPalabras claves:2-methyltetrahydrofuran, Cyclopentyl methyl ether, Green solvents, Peptide synthesis, Solid-phase peptide synthesisAutores:Acosta G.A., Alberício F., B. G. De la Torre, El-Faham A., Govender T., Jad Y.E., Khattab S.N., Kruger H.G.Fuentes:scopusA new strategy for solid-phase depsipeptide synthesis using recoverable building blocks
ArticleAbstract: (Chemical Equation Presented) The technique of choice for synthesis of small-scale depsipeptides isPalabras claves:Autores:Alberício F., Burger K., Jan Spengler, Ruíz-Rodríguez J.Fuentes:googlescopusCuAAC: An Efficient Click Chemistry Reaction on Solid Phase
ReviewAbstract: Click chemistry is an approach that uses efficient and reliable reactions, such as Cu(I)-catalyzed aPalabras claves:alkyne, azide, Click Chemistry, CuAAC, solid-phaseAutores:Alberício F., Castro V., Hortensia Rodriguez CabreraFuentes:googlescopusAmide Formation: Choosing the Safer Carbodiimide in Combination with OxymaPure to Avoid HCN Release
ArticleAbstract: It has been reported that DIC can react with OxymaPure to render an oxadiazole compound with the conPalabras claves:Autores:Acosta G.A., Alberício F., B. G. De la Torre, El-Faham A., Luna O., Manne S.R., Orosz G., Royo M.Fuentes:scopusAmino-Li-Resin—A Fiber Polyacrylamide Resin for Solid-Phase Peptide Synthesis
ArticleAbstract: Amino-Li-resin is a new and unique polyacrylamide resin presented in the form of fibers and is foundPalabras claves:amino-Li-resin, fibers, Polyacrylamide, Solid-phase peptide synthesisAutores:Akintayo D.C., Alberício F., B. G. De la Torre, Li Y.Fuentes:scopusGreen solid-phase peptide synthesis 4. γ-Valerolactone and N-formylmorpholine as green solvents for solid phase peptide synthesis
ArticleAbstract: Herein, we report the use of γ-valerolactone (GVL) and N-formylmorpholine (NFM) as DMF substitutes iPalabras claves:Green solvents, GVL, NFM, polystyrene resin, Solid-phase peptide synthesisAutores:Alberício F., B. G. De la Torre, El-Faham A., Jad Y.E., Kumar A.Fuentes:scopusGreening the Solid-Phase Peptide Synthesis Process. 2-MeTHF for the Incorporation of the First Amino Acid and Precipitation of Peptides after Global Deprotection
ArticleAbstract: In solid-phase peptide synthesis, dichloromethane is the predominant solvent used to incorporate thePalabras claves:2-MeTHF, Dipeptide formation, incorporation, precipitation, Racemization, Solid-phase peptide synthesisAutores:Al Musaimi O., Alberício F., B. G. De la Torre, Basso A., Collins J.M., El-Faham A., Jad Y.E., Kumar A.Fuentes:scopusExploiting azido-dichloro-triazine as a linker for regioselective incorporation of peptides through their N, O, S functional groups
ArticleAbstract: In the field of bioconjugation, linker development has witnessed massive growth in recent years. 2,4Palabras claves:Bioconjuation, Linker, Orthogonal chemoselectivity, Orthogonality, Solid-phase peptide synthesisAutores:Alberício F., B. G. De la Torre, El-Faham A., Kumar A., Sharma A.Fuentes:scopus