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Asymmetric synthesis of α-unsubstituted β-hydroxy acids
ReviewAbstract: α-Unsubstituted β-hydroxy acid (3-hydroxycarboxylic acids) are constituents of various natural produPalabras claves:3-hydroxycarboxylic acids, Arndt-Eister homologation, Asymmetric aldol reactions, Asymmetric reduction, Cyclic sulfates, Cyclic sulfites, Reductive cleavage, Reformatsky reactions, β-lactonesAutores:Alberício F., Jan SpenglerFuentes:googlescopusBioconjugation through Mesitylene Thiol Alkylation
ArticleAbstract: The design and generation of complex multifunctional macromolecular structures by bioconjugation isPalabras claves:Autores:Alberício F., Cuevas C., Domínguez J.M., Hortensia Rodriguez Cabrera, Pérez-Chacon G., Ramos-Tomillero I., Sánchez‐Madrid F., Somovilla-Crespo B., Zapata J.M.Fuentes:googlescopus3,4-Dihydro-2(1H)-Pyridones as Building Blocks of Synthetic Relevance
ReviewAbstract: 3,4-Dihydro-2(1H)-pyridones (3,4-DHPo) and their derivatives are privileged structures, which has inPalabras claves:1,4-DHPs, 3,4-DHPo, multicomponent reaction, nonconventional synthesis, synthetic precursorsAutores:Alberício F., Castro V., Hortensia Rodriguez Cabrera, Ruth Oropeza, Sisa P. Chalán-Gualán, Suárez Navarro M.Fuentes:googlescopusA comparative evaluation of biological activities and bioactive compounds of the seagrasses Zostera marina and Zostera noltei from southern Portugal
ArticleAbstract: This work assessed the antioxidant potential, acetylcholinesterase (AChE) inhibition and the in vitrPalabras claves:Cytotoxicity, Oxidative Stress, PUFA, rosmarinic acid, SeagrassesAutores:Alberício F., Barreira L., Custódio L., Engelen A.H., Hortensia Rodriguez Cabrera, Laukaityte S., Pereira H., Rodrigues M.J., Varela J., Vizetto-Duarte C.Fuentes:googlescopusA new strategy for solid-phase depsipeptide synthesis using recoverable building blocks
ArticleAbstract: (Chemical Equation Presented) The technique of choice for synthesis of small-scale depsipeptides isPalabras claves:Autores:Alberício F., Burger K., Jan Spengler, Ruíz-Rodríguez J.Fuentes:googlescopusA novel protecting/activating strategy for β-hydroxy acids and its use in convergent peptide synthesis
ArticleAbstract: (Chemical Equation Presented) β-Hydroxy acids were reacted with hexafluoroacetone and carbodiimidesPalabras claves:Autores:Alberício F., Burger K., Jan Spengler, Royo M., Ruíz-Rodríguez J., Winter M., Yraola F.Fuentes:googlescopusCuAAC: An Efficient Click Chemistry Reaction on Solid Phase
ReviewAbstract: Click chemistry is an approach that uses efficient and reliable reactions, such as Cu(I)-catalyzed aPalabras claves:alkyne, azide, Click Chemistry, CuAAC, solid-phaseAutores:Alberício F., Castro V., Hortensia Rodriguez CabreraFuentes:googlescopusCysteine-S-trityl a key derivative to prepare N-methyl cysteines
ArticleAbstract: S-Trt Cys are used as precursors for the synthesis of protected NMe-Cys. N-Methylation of Alloc-Cys(Palabras claves:Autores:Alberício F., Bayó-Puxan N., Jan Spengler, Marcucci E., Tulla-Puche J.Fuentes:googlescopusApplication of hexafluoroacetone as protecting and activating reagent in solid phase peptide and depsipeptide synthesis
ArticleAbstract: Hexafluoroacetone-protected/activated hydroxy acids [2,2- bis(trifluoromethyl)-1,3-dioxolan-4-ones]Palabras claves:Bidentate reagents, Citramalic acid, Hexafluoroacetone, Tetrahydroisoquinoline carboxylic acidAutores:Alberício F., Burger K., Cupido T., Jan Spengler, Ruiz J.Fuentes:googlescopusAmide-to-ester substitution in coiled coils: The effect of removing hydrogen bonds on protein structure
ArticleAbstract: (Figure Presented) The latest twist: The effect of backbone H-bonding on the stability of proteins wPalabras claves:Depsipeptides, Hydrogen bonds, molecular dynamics, Protein folding, SuperhelicesAutores:Alberício F., Baldauf C., Jan Spengler, Koksch B., Pisabarro M., Scheike J.Fuentes:googlescopus