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Article(5)
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Angewandte Chemie - International Edition(1)
Chemical Communications(1)
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Amide-to-ester substitution in coiled coils: The effect of removing hydrogen bonds on protein structure
ArticleAbstract: (Figure Presented) The latest twist: The effect of backbone H-bonding on the stability of proteins wPalabras claves:Depsipeptides, Hydrogen bonds, molecular dynamics, Protein folding, SuperhelicesAutores:Alberício F., Baldauf C., Jan Spengler, Koksch B., Pisabarro M., Scheike J.Fuentes:googlescopusIncorporation of the α-mercapto acid unit into peptides
ArticleAbstract: Incorporation of α-mercapto acid units into the backbone of potential drug candidates improves the mPalabras claves:Acylations, Dielectrophiles, Hexafluoroacetone, Peptides, Thiols, Thiomalic acidAutores:Alberício F., Burger K., Haas A., Jan Spengler, Pumpor K.Fuentes:googlescopusThe backbone N-(4-azidobutyl) linker for the preparation of peptide chimera
ArticleAbstract: A robust synthetic strategy for the introduction of the N-(4-azidobutyl) linker into peptides usingPalabras claves:Autores:Adan J., Alberício F., Fernandez-Llamazares A.I., García J., Jan Spengler, Meunier D., Mitjans F.Fuentes:googlescopusThe potential of N-alkoxymethyl groups as peptide backbone protectants
ArticleAbstract: In this study, the potential of N-alkoxymethyl groups as protectants for the peptide backbone has bePalabras claves:Backbone N-alkylation, Backbone protecting groups, N-Alkoxymethyl, Peptides, SPPSAutores:Alberício F., Fernandez-Llamazares A.I., Jan SpenglerFuentes:googlescopusThe synthesis of an EDTA-like chelating peptidomimetic building block suitable for solid-phase peptide synthesis
ArticleAbstract: A novo trifunctional EDTA-like peptidomimetic amino acid is described. This unique building block, wPalabras claves:Autores:Alberício F., Barker M., García J., Jan Spengler, Macias M.J., Schelhorn C.Fuentes:googlescopus