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Forensic Science International: Genetics Supplement Series(2)
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Frontiers in Pharmacology(1)
Association of genetic variants of membrane receptors related to recognition and induction of immune response with Helicobacter pylori infection in Ecuadorian individuals
ArticleAbstract: Helicobacter pylori (Hp) has a worldwide distribution showing its higher prevalence of infection inPalabras claves:Autores:Alejandro Cabrera-Andrade, Andrés López-Cortés, Cesar Paz-y-Miño, Gabriela Fernanda Jaramillo-Koupermann, María José G. Muñoz, O. Rodriguez, Paola E. LeoneFuentes:googlescopusAncestry characterization of Ecuador's Highland mestizo population using autosomal AIM-INDELs
ArticleAbstract: Ancestry Informative Insertion-Deletion markers have been used as a tool to infer the origin of popuPalabras claves:admixture, Ancestry, EcuadoriansAutores:Alejandro Cabrera-Andrade, Ana Karina Zambrano, Andrés López-Cortés, Anibal Gaviria, Cesar Paz-y-Miño, Fiallo G., Gruezo C., Jennyfer M. García-Cárdenas, Margarita Vela, Paola E. Leone, S. CobosFuentes:googlescopusAncestry study in Ecuadorian population with multiple myeloma
ArticleAbstract: Multiple myeloma (MM) is a type of hematologic cancer that mainly affects the afro-descendant populaPalabras claves:Ancestry, ECUADOR, Multiple myelomaAutores:Alejandro Cabrera-Andrade, Ana Karina Zambrano, Andrés López-Cortés, Cesar Paz-y-Miño, D. A. González, Jennyfer García, Jennyfer M. García-Cárdenas, P. Guevara-Ramírez, Paola E. LeoneFuentes:googlescopusA multi-objective approach for anti-osteosarcoma cancer agents discovery through drug repurposing
ArticleAbstract: Osteosarcoma is the most common type of primary malignant bone tumor. Although nowadays 5-year surviPalabras claves:Drug repositioning, Machine learning, Multi-objective model, Osteosarcoma, Virtual ScreeningAutores:Alejandro Cabrera-Andrade, Andrés López-Cortés, Eduardo Tejera, Gabriela Fernanda Jaramillo-Koupermann, González‐díaz H., Munteanu C.R., Sierra A.P., Yunierkis Perez-CastilloFuentes:scopusA multi-objective approach for drug repurposing in preeclampsia
ArticleAbstract: Preeclampsia is a hypertensive disorder that occurs during pregnancy. It is a complex disease with uPalabras claves:Drugs repurposing, Machine learning, Multi-objective models, PreeclampsiaAutores:Alejandro Cabrera-Andrade, Andrea Chamorro, Eduardo Tejera, Sánchez M.E., Yunierkis Perez-CastilloFuentes:scopusGene prioritization, communality analysis, networking and metabolic integrated pathway to better understand breast cancer pathogenesis
ArticleAbstract: Consensus strategy was proved to be highly efficient in the recognition of gene-disease association.Palabras claves:Autores:Alejandro Cabrera-Andrade, Andrés López-Cortés, Cesar Paz-y-Miño, Eduardo Tejera, González‐díaz H., Munteanu C.R., Sierra A.P., Stephen Jones Barigye, Yunierkis Perez-CastilloFuentes:googlescopusDrugs Repurposing Using QSAR, Docking and Molecular Dynamics for Possible Inhibitors of the SARS-CoV-2 M<sup>pro</sup> Protease
ArticleAbstract: Wuhan, China was the epicenter of the first zoonotic transmission of the severe acute respiratory syPalabras claves:covid-19, Drugs repurposing, molecular dynamics, QSAR, SARS-COV-2Autores:Alejandro Cabrera-Andrade, Andrés López-Cortés, Eduardo Tejera, Munteanu C.R., Yunierkis Perez-CastilloFuentes:googlescopusSalivary MicroRNAs for Early Detection of Head and Neck Squamous Cell Carcinoma: A Case-Control Study in the High Altitude Mestizo Ecuadorian Population
ArticleAbstract: Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer with the highest incidPalabras claves:Autores:Alejandro Cabrera-Andrade, Andrés López-Cortés, Carolina Salazar-Ruales, Cesar Paz-y-Miño, Jennyfer M. García-Cárdenas, Jessica Viviana Arguello, P. Guevara-Ramírez, Paola E. Leone, Peralta P.Fuentes:scopusPulmonary Inflammatory Response in Lethal COVID-19 Reveals Potential Therapeutic Targets and Drugs in Phases III/IV Clinical Trials
ArticleAbstract: Background: It is imperative to identify drugs that allow treating symptoms of severe COVID-19. RespPalabras claves:clinical trials, drugs, lethal COVID-19, pulmonary inflammatory response, single nucleus RNA sequencingAutores:Alejandro Cabrera-Andrade, Álvaro A. Pérez-Meza, Ana María Gómez-Jaramillo, Andrea Abad-Sojos, Andrea V. Jácome, Andrés López-Cortés, Andy Pérez-Villa, Ángela León-Cáceres, Antonella Vera-Guapi, Ariana León-Sosa, Cevallos-Robalino D., Echeverría-Garcés G., Esteban Ortiz-Prado, Estefanía Abarca, Fernanda Arias-Erazo, Isaac Armendáriz-Castillo, Jennyfer M. García-Cárdenas, Jhommara Bautista, Katherine Simbaña-Rivera, Lourdes Puig San Andrés, Luis Fuenmayor-González, Morillo A., Nieto-Jaramillo K., Nikolaos C. Kyriakidis, P. Guevara-Ramírez, Quiñones L.A., Ramos-Medina M.J., Santiago Xavier Guerrero, Verónica YumicebaFuentes:scopusStudy of the Huntington's disease IT-15 gene in different ethnic groups in Ecuador
ArticleAbstract: This study aims to establish the current state of the IT-15 (HTT) gene in different Ecuadorian ethniPalabras claves:Autosomal dominant, CAG repeats, Huntington's disease, NeurodegenerationAutores:Alejandro Cabrera-Andrade, Andrés López-Cortés, Carolina Salazar-Ruales, Cesar Paz-y-Miño, Cristian D. Cusco-Cuzco, E. Eras, Jennyfer M. García-Cárdenas, Juan P. Domínguez-Enríquez, Navarrete Socasi D.C., Paola E. Leone, Rodriguez P C., Victor H. Pavón-RealpeFuentes:scopus