Documentos de Harrison Castro

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Mostrando 10 resultados de: 80

Compostos, composição farmacêutica, e, métodos de tratamento de obesidade, de tratamento de resistência à insulina, de tratamento de diabetes tipo ii, de tratamento de atrofia …

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Abstract: DNCYBUMDUBHIJZ-UHFFFAOYSA-N 1H-pyrimidin-6-one Chemical compound data: image/svg+xml; base64, PD94bW

Azacyclic compounds, processes for their preparation and pharmaceutical compositions containing them

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Abstract: 125000001997 phenyl group Chemical group data: image/svg+xml; base64, PD94bWwgdmVyc2lvbj0nMS4wJyBlbm

Benzodiazepine derivatives as APP modulators

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Abstract: (57) ABSTRACT A novel class of 1, 4-and 1.5-benzodiazepines of formula (I) is disclosed. The compoun

Antitumor activity of the novel oral highly selective Wee1 inhibitor Debio 0123

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Abstract: Background: The Wee1 tyrosine kinase is activated upon DNA damage and regulates the G2-M cell cycle

(4, 5, 6, 7-tetrahydro-1-H-indol-7-yl) acetic acid derivatives for treatment of Alzheimer's disease

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Abstract: Statistical Manual of Mental Disorders, 4" ed., published by the American Psychiatric Association (D

3, 4-Fused cyclohexyl sulfones as γ-secretase inhibitors

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Abstract: The 3,4-fused sulfamides, sulfonamides and sulfone have been identified as highly potent γ-secretase

3-Substituted gem-cyclohexane sulfone based γ-secretase inhibitors for Alzheimer’s disease: Conformational analysis and biological activity

Other

Abstract: Previously, chemistry effort on the gem-cyclohexane series of γ-secretase inhibitors has focused on

4,4-Disubstituted Piperidine High-Affinity NK1 Antagonists: Structure−Activity Relationships and in Vivo Activity

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Abstract: Previously reported studies from these laboratories described the design of a novel series of high-a

4-Arylmethyloxymethyl piperidines as tachykinin antagonsits

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Abstract: This application is A371 of PCT/GB93/02214 filed Oct. 27, 1993. This invention relates to a class of

4-Substituted cyclohexyl sulfones as potent, orally active γ-secretase inhibitors

Other

Abstract: The protease γ-secretase plays a pivotal role in the synthesis of pathogenic amyloid-β in Alzheimer’

Mostrando 10 resultados de: 80

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Compostos, composição farmacêutica, e, métodos de tratamento de obesidade, de tratamento de resistência à insulina, de tratamento de diabetes tipo ii, de tratamento de atrofia …

Azacyclic compounds, processes for their preparation and pharmaceutical compositions containing them

Benzodiazepine derivatives as APP modulators

Antitumor activity of the novel oral highly selective Wee1 inhibitor Debio 0123

(4, 5, 6, 7-tetrahydro-1-H-indol-7-yl) acetic acid derivatives for treatment of Alzheimer's disease

3, 4-Fused cyclohexyl sulfones as γ-secretase inhibitors

3-Substituted gem-cyclohexane sulfone based γ-secretase inhibitors for Alzheimer’s disease: Conformational analysis and biological activity

4,4-Disubstituted Piperidine High-Affinity NK1 Antagonists: Structure−Activity Relationships and in Vivo Activity

4-Arylmethyloxymethyl piperidines as tachykinin antagonsits

4-Substituted cyclohexyl sulfones as potent, orally active γ-secretase inhibitors