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High-throughput preparation of alkyl 4-aryl substituted-2-methyl-6-thioxo- 1,4,5,6-tetrahydropyridine-3-carboxylates under microwave irradiation
ArticleAbstract: An efficient high-throughput synthesis of 4-aryl substituted 1,4,5,6-tetrahydro-2-methyl-6-thioxopyrPalabras claves:heterocycles, Lawesson's reagent, Microwave irradiation, Theoretical calculation, ThiopyridonesAutores:Alberício F., Coro J., Hortensia Rodriguez Cabrera, Lam A., Martín N., Rodríguez-Salarichs J., Salfrán E., Suárez Navarro M.Fuentes:googlescopusEmpowerment of women in science: Myth or reality
OtherAbstract:Palabras claves:Autores:Hortensia Rodriguez CabreraFuentes:googlescopusFrom Ugi Multicomponent Reaction to Linkers for Bioconjugation
ArticleAbstract: Bioconjugation is a key approach for the development of novel molecular entities with clinical appliPalabras claves:Autores:Alberício F., Cuevas C., Domínguez J.M., Hortensia Rodriguez Cabrera, Pérez-Chacon G., Ramos-Tomillero I., Sánchez‐Madrid F., Somovilla-Crespo B., Zapata J.M.Fuentes:googlescopusEco-friendly methodology to prepare N-heterocycles related to dihydropyridines: Microwave-assisted synthesis of alkyl 4-arylsubstituted-6- chloro-5-formyl-2-methyl-1,4-dihydropyridine-3-carboxylate and 4-arylsubstituted-4,7-dihydrofuro[3,4-b]pyridine-2,5(1H,3H)-dione
ArticleAbstract: Here we describe the efficient synthesis of alkyl 4-arylsubstituted-6- chloro-5- formyl-2-methyl-1,4Palabras claves:Dihydropyridines, Green Chemistry, MICROWAVEAutores:Alberício F., Hortensia Rodriguez Cabrera, Martín N., Martín O., Suárez Navarro M.Fuentes:googlescopusEffect of thiadiazine derivatives on intracellular amastigotes of Leishmania amazonensis
ArticleAbstract: Current therapy for leishmaniasis is not satisfactory. We describe the in vitro antiproliferative efPalabras claves:AMASTIGOTES, LEISHMANIA, thiadiazineAutores:Álvarez A.M.M., Fidalgo L.M., Géigel L.F., Hortensia Rodriguez Cabrera, Navarro M.S., Pineiro R.P.Fuentes:googlescopusEfficient sonochemical synthesis of alkyl 4-aryl-6-chloro-5-formyl-2- methyl-1,4-dihydropyridine-3-carboxylate derivatives
ArticleAbstract: A facile, efficient and environment-friendly protocol for the synthesis of 6-chloro-5-formyl-1,4-dihPalabras claves:1,4-Dihydropyridine derivatives, Sonochemistry, ultrasound irradiation, Vilsmeier-Haack reactionAutores:Coro J., Enrique Ruiz-Reyes, Hortensia Rodriguez Cabrera, Martín N., Martínez-Álvarez R., Niebla V., Novoa De Armas H., Rodríguez A., Suárez Navarro M.Fuentes:googlescopusDevelopment of a novel virtual screening cascade protocol to identify potential trypanothione reductase inhibitors
ArticleAbstract: The implementation of a novel sequential computational approach that can be used effectively for virPalabras claves:Autores:Andrew L.C., Burgos A., Fairlamb A.H., Hortensia Rodriguez Cabrera, Jones D.C., Perez-Pineiro R., Suárez Navarro M., Wishart D.S.Fuentes:googlescopusCuAAC: An Efficient Click Chemistry Reaction on Solid Phase
ReviewAbstract: Click chemistry is an approach that uses efficient and reliable reactions, such as Cu(I)-catalyzed aPalabras claves:alkyne, azide, Click Chemistry, CuAAC, solid-phaseAutores:Alberício F., Castro V., Hortensia Rodriguez CabreraFuentes:googlescopus3,4-Dihydro-2(1H)-Pyridones as Building Blocks of Synthetic Relevance
ReviewAbstract: 3,4-Dihydro-2(1H)-pyridones (3,4-DHPo) and their derivatives are privileged structures, which has inPalabras claves:1,4-DHPs, 3,4-DHPo, multicomponent reaction, nonconventional synthesis, synthetic precursorsAutores:Alberício F., Castro V., Hortensia Rodriguez Cabrera, Ruth Oropeza, Sisa P. Chalán-Gualán, Suárez Navarro M.Fuentes:googlescopusA Novel Network Science and Similarity-Searching-Based Approach for Discovering Potential Tumor-Homing Peptides from Antimicrobials
ArticleAbstract: Peptide-based drugs are promising anticancer candidates due to their biocompatibility and low toxiciPalabras claves:Cáncer, centrality measure, chemical space network, Complex network, group fusion, in silico drug discovery, motif discovery, Similarity searching, starPep toolbox software, tumor-homing peptideAutores:Agüero-Chapin G., Aguilera-Mendoza L., Antunes A., Hortensia Rodriguez Cabrera, Martinez-Rios F.O., Maylin Romero, Yovani Marrero-PonceFuentes:googlescopus