Mostrando 10 resultados de: 26
Filtros aplicados
Publisher
Chimica Oggi/Chemistry Today(3)
Amino Acids(2)
Helvetica Chimica Acta(2)
Advances in Protein Chemistry and Structural Biology(1)
Antibiotics(1)
Área temáticas
Farmacología y terapéutica(13)
Bioquímica(6)
Química analítica(6)
Química orgánica(5)
Enfermedades(3)
Origen
scopus(26)
Chemical platforms for peptide vaccine constructs
Book PartAbstract: Knowledge of the sequences and structures of proteins from pathogenic microorganisms has been put toPalabras claves:Chemical approaches, MAPS, Peptide epitopes, Synthesis, VaccineAutores:Alberício F., B. G. De la Torre, Cherkupally P., Govender T., Kruger H.G., Ramesh S.Fuentes:scopusCombining solid phase synthesis and chromatographic purification for efficient peptide manufacture
ArticleAbstract: In recent years, peptides have gained an important position in the drug arena for a variety of treatPalabras claves:Oligos-peptides, Peptide purification, Peptide synthesis, Polystyrene resins, Solid phase peptide synthesisAutores:Alberício F., B. G. De la Torre, Basso A., Musaimi O.A.L., Serban S., Summers B.D.Fuentes:scopus2022 FDA TIDES (Peptides and Oligonucleotides) Harvest
ArticleAbstract: A total of 37 new drug entities were approved in 2022; although that year registered the lowest numbPalabras claves:drugs, FDA, gadopiclenol, lutetium ( Lu) vipivotide tetraxetan 177, Oligonucleotides, Peptides, terlipressin, tirzepatide, vutrisiranAutores:Al Musaimi O., Al Shaer D.M., Alberício F., B. G. De la TorreFuentes:scopus6-(bromomaleimido)hexanoic acid as a connector for the construction of multiple branched peptide platforms
ArticleAbstract: We report on a novel and user-friendly platform based on a bromomaleimide moiety to obtain branchedPalabras claves:Autores:Alberício F., B. G. De la Torre, Cherkupally P., Govender T., Kruger H.G., Ramesh S.Fuentes:scopusA BODIPY-embedding miltefosine analog linked to cell-penetrating Tat(48-60) peptide favors intracellular delivery and visualization of the antiparasitic drug
ArticleAbstract: Therapeutic application of many drugs is often hampered by poor or denied access to intracellular taPalabras claves:BODIPY, cell-penetrating peptide, Dual fluorescent labeling, Miltefosine, Monitoring of intracellular drug delivery, Reversion of resistanceAutores:Abengózar M.Á., Amat-Guerri F., Andreu D., B. G. De la Torre, Hornillos V., Luque-Ortega J.R., Rivas L., Ulises Acuña A.Fuentes:scopusA flexible method for the fabrication of gold nanostructures using oligonucleotide derivatives
ArticleAbstract: Several linear and branched DNA structures from 80-200 nm with a biotine molecule in the middle havePalabras claves:DNA nanobiotechnology, Gold nanoparticles, self-assemblyAutores:Aviñó A., B. G. De la Torre, DiSalvo A., Eritja R., Fitzmaurice D., Iacopino D., Maninng B., Ongaro A., Stanca S.E.Fuentes:scopusActive targeting of CD4<sup>+</sup>T lymphocytes by PEI-capped, peptide-functionalized gold nanoparticles
ArticleAbstract: Active targeting is a promising approach for the treatment of viral infections. In particular, site-Palabras claves:active targeting, anti-CD4 peptide, gold nanoparticle, hiv, UptakeAutores:Alberício F., B. G. De la Torre, Kruger H.G., Ncobeni N., Parboosing R.Fuentes:scopusActivity of cecropin A-melittin hybrid peptides against colistin-resistant clinical strains of Acinetobacter baumannii: Molecular basis for the differential mechanisms of action
ArticleAbstract: Acinetobacter baumannii has successfully developed resistance against all common antibiotics, includPalabras claves:Autores:Andreu D., B. G. De la Torre, Fernández-Reyes M., Pachón J., Pachón-Ibañez M.E., Rivas L., Rodríguez-Hernández M.J., Saugar J.M.Fuentes:scopusGREEN CIRCULAR ECONOMY APPLIED TO PEPTIDE SYNTHESIS
ArticleAbstract: While the focus of industry was once to cover people’s needs, it is now imperative to address how toPalabras claves:Circular economy, Green Chemistry, Oligonucleotides, recycling, redesigning, Solid-phase peptide synthesis, SustainabilityAutores:Alberício F., B. G. De la Torre, Musaimi O.A.L., Shaer D.A.L.Fuentes:scopusNucleic acid delivery by cell penetrating peptides derived from dengue virus capsid protein: Design and mechanism of action
ArticleAbstract: Cell penetrating peptides (CPPs) can be used as drug delivery systems for different therapeutic molePalabras claves:capsid protein, cell penetrating peptide, Dengue Virus, Gene therapy, time-resolved flow cytometryAutores:Andreu D., B. G. De la Torre, Castanho M.A.R.B., Da Poian A.T., Freire J.M., Rego De Figueiredo I., Santos N.C., Veiga A.S.a.Fuentes:scopus