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Chemical platforms for peptide vaccine constructs
Book PartAbstract: Knowledge of the sequences and structures of proteins from pathogenic microorganisms has been put toPalabras claves:Chemical approaches, MAPS, Peptide epitopes, Synthesis, VaccineAutores:Alberício F., B. G. De la Torre, Cherkupally P., Govender T., Kruger H.G., Ramesh S.Fuentes:scopusChemoselective Disulfide Formation by Thiol-Disulfide Interchange in SIT-Protected Cysteinyl Peptides
ArticleAbstract: Chemoselective disulfide formation is accomplished through a thiol-disulfide interchange approach usPalabras claves:Autores:Alberício F., B. G. De la Torre, Chakraborty A.Fuentes:scopusCleaving protected peptides from 2-chlorotrityl chloride resin. Moving away from dichloromethane
ArticleAbstract: In recent years, the work of various research groups has allowed the substitution of the hazardous sPalabras claves:Autores:Al Musaimi O., Alberício F., Alhassan M., B. G. De la Torre, Collins J.M.Fuentes:scopusDiethylphosphoryl-oxymab (DEPO-B) as a solid coupling reagent for amide bond formation
ArticleAbstract: A new phosphonium based coupling reagent DEPO-B has been synthesized from 5-(hydroxyimino)-1,3-dimetPalabras claves:coupling reagent, Diethylphosphoryl-OxymaB, Hydrolytic stability, Phosphonium salts, SOLUBILITYAutores:Alberício F., B. G. De la Torre, El-Faham A., Jad Y.E., Kumar A.Fuentes:scopusCrystal structure and theoretical investigation of thiobarbituric acid derivatives as nonlinear optical (NLO) materials
ArticleAbstract: Here we report on the crystal structure of three enamine/imine TBA derivatives (1−3). Since the deriPalabras claves:Crystals, DFT, Enamine/imine tautomer, Hyperpolarizability, NLOAutores:Al-Majid A.M., Al-Rasheed H.H., Alberício F., B. G. De la Torre, Barakat A., Choudhary M.I., El-Faham A., Sharma A., Yousuf S.Fuentes:scopusCrystal structure, spectroscopic studies and theoretical studies of thiobarbituric acid derivatives: understanding the hydrogen-bonding patterns
ArticleAbstract: In addition to their wide-ranging applications in the pharmaceutical industry, thiobarbituric acid (Palabras claves:Crystal structure, DFT calculations, IR spectroscopy, Thiobarbituric acid, Transition state, UV spectroscopy, X-ray crystallographyAutores:Alberício F., Almarhoon Z.M., B. G. De la Torre, El-Faham A., Noki S., Sharma A., Zamisa S.J.Fuentes:scopusAmino-Li-Resin—A Fiber Polyacrylamide Resin for Solid-Phase Peptide Synthesis
ArticleAbstract: Amino-Li-resin is a new and unique polyacrylamide resin presented in the form of fibers and is foundPalabras claves:amino-Li-resin, fibers, Polyacrylamide, Solid-phase peptide synthesisAutores:Akintayo D.C., Alberício F., B. G. De la Torre, Li Y.Fuentes:scopusGreen Solid-Phase Peptide Synthesis 2. 2-Methyltetrahydrofuran and Ethyl Acetate for Solid-Phase Peptide Synthesis under Green Conditions
ArticleAbstract: N,N-Dimethylformamide (DMF), N-methyl-2-pyrrolidone, and dichloromethane (DCM) are the most widely uPalabras claves:2-MeTHF, Green Chemistry, Peptide aggregation, Polyethylene glycol resins, Solid-phase peptide synthesis, solid-phase synthesisAutores:Acosta G.A., Alberício F., B. G. De la Torre, El-Faham A., Govender T., Jad Y.E., Kruger H.G.Fuentes:scopusGreening the Solid-Phase Peptide Synthesis Process. 2-MeTHF for the Incorporation of the First Amino Acid and Precipitation of Peptides after Global Deprotection
ArticleAbstract: In solid-phase peptide synthesis, dichloromethane is the predominant solvent used to incorporate thePalabras claves:2-MeTHF, Dipeptide formation, incorporation, precipitation, Racemization, Solid-phase peptide synthesisAutores:Al Musaimi O., Alberício F., B. G. De la Torre, Basso A., Collins J.M., El-Faham A., Jad Y.E., Kumar A.Fuentes:scopusExploring the orthogonal chemoselectivity of 2,4,6-trichloro-1,3,5-triazine (TCT) as a trifunctional linker with different nucleophiles: Rules of the game
ArticleAbstract: The study involves exploring the three orthogonal sites for aromatic nucleophilic substitution in cyPalabras claves:density functional theory, Electrostatic potential maps, NBO calculations, S-triazine, Triorthogonal linkerAutores:Alberício F., B. G. De la Torre, El-Faham A., Sharma A.Fuentes:scopus