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CIGB-300, a novel proapoptotic peptide that impairs the CK2 phosphorylation and exhibits anticancer properties both in vitro and in vivo
ArticleAbstract: Protein Kinase CK2 is a serine-threonine kinase frequently deregulated in many human tumors. Here, wPalabras claves:apoptosis, Cancer targeted therapy, Casein kinase 2Autores:Acevedo B.E., Alonso D.F., Ariosa J., Bacardí D.M., Baladron I., Besada-Pérez V., Betancourt L., Castellanos L.R., Cosme K., Cruz M., Díaz A., Falcón-Cama V., Farina H., Garay H.E., Gil J., Gómez D., Gómez R., González L.J., Hernández I., Herrera L., López C., López-Mola E., López-Saura P.A., Marcelo J.L., Mendoza O., Perea-Rodríguez S.E., Perera Y., Puchades Y., Reyes O., Rodriguez A., Sánchez A., Santana A., Serrano J.M., Sigman H., Silva R., Solares M., Thelvia I. Ramos Gómez, Valenzuela-Silva C.M.Fuentes:googlescopusIdentification of the first antagonist peptide that inhibits biological effects of interleukin-15
ArticleAbstract: Interleukin-15 (IL-15) is a pro-inflammatory cytokine that is expressed in several autoimmune and inPalabras claves:Alpha receptor, antagonist, Cytokine, IL-15, peptideAutores:Alexey Llópiz-Arzuaga, Altruda F., Ancisar J.A., Arrieta C.A., Cabrales A., Chico A., Estévez M., Garay H.E., Geronimo H., Guillén-Nieto G.E., Machado A.C., Noda J., Ojeda M., Perea-Rodríguez S.E., Reyes O., Rodríguez-Álvarez Y., Sánchez A., Santos-Savio A., Silengo L., Suaréz J., Vázquez M.Fuentes:googlescopusSolid phase synthesis of 3-(5'-carboxypentyl)-5-substituted tetrahydro- 2H-1,3,5-thiadiazin-2-thione derivatives
ArticleAbstract: The solid phase synthesis of 3-(5'-carboxypentyl)-5-substituted tetrahydro-2H-1,3,5-thiadiazin-2-thiPalabras claves:Resins amino acids, solid-phase synthesis, Thiadiazin-2-thionesAutores:Cruz L.J., Garay H.E., Hortensia Rodriguez Cabrera, Molero-Vilchez M.D., Ochoa C., Perez-Pineiro R., Reyes O., Suárez Navarro M.Fuentes:googlescopusSolid-phase synthesis of 4-aryl substituted 5-carboxy-6-methyl-3,4-dihydropyridones
ArticleAbstract: Substituted 3,4-dihydro-2-pyridones have been efficiently prepared by solid-phase synthesis using WaPalabras claves:5-Carboxy-6-methyl-3,4-dihydropyridones, solid-phase synthesis, Wang resinAutores:Cruz L.J., Garay H.E., Hortensia Rodriguez Cabrera, Martín N., Perez-Pineiro R., Reyes O., Seoane C., Suárez Navarro M., Verdecia Y.Fuentes:googlescopus