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A criterion for the selection of monophasic solvents for enzymatic synthesis
ArticleAbstract: Penicillin acylase can be used for the production of β-lactamic antibiotics which have a wide rangePalabras claves:Antibiotic, Enzyme stability, Equilibrium-controlled synthesis, Organic solvent selection, Penicillin acylaseAutores:Cristina M. Rosell, Fernandez‐Lafuente R., Guisan J.M., Terreni M.Fuentes:scopusAdditional stabilization of penicillin G acylase-agarose derivatives by controlled chemical modification with formaldehyde
ArticleAbstract: We have tested the effect of chemical modifications with formaldehyde on the activity/stability of iPalabras claves:chemical modification of proteins, Enzyme stabilization, formaldehyde treatment of enzymes, immobilization-stabilization of enzymesAutores:Alvaro G., Cristina M. Rosell, Fernandez‐Lafuente R., Guisan J.M.Fuentes:scopusModification of enzyme properties by the use of inhibitors during their stabilisation by multipoint covalent attachment
ArticleAbstract: The effect of a number of inhibitors adsorbed at the active site of penicillin acylase during immobiPalabras claves:inhibitor, Penicillin acylase, StabilisationAutores:Cristina M. Rosell, Fernandez‐Lafuente R., Guisan J.M.Fuentes:scopusModulation of the properties of penicillin G acylase by acyl donor substrates during N-protection of amino compounds
ArticleAbstract: The rates and yields in the synthesis of N-protected amino compounds catalyzed by penicillin G acylaPalabras claves:Enzyme modulation, Enzymes (in fine chemistry), Optically pure compound synthesis, Penicillin G acylase, Protection of amino compoundsAutores:Cristina M. Rosell, Fernandez‐Lafuente R., Guisan J.M.Fuentes:scopusSelective Enzymatic Oxidations by using Oxygen as oxidizing agent: Immobilization and Stabilization of FNR, a NADP<sup>+</sup> regenerating enzyme
ArticleAbstract: We have developed a new strategy to prepare very active and very stable derivatives of the enzyme fePalabras claves:Autores:Bes T., Cristina M. Rosell, Fernandez‐Lafuente R., Gomez-Moreno C., Guisén J.M.Fuentes:scopusThe use of stabilised penicillin acylase derivatives improves the design of kinetically controlled synthesis
ArticleAbstract: The advantages of the use of stabilised derivatives in the kinetically controlled synthesis catalysePalabras claves:Enzymes, Immobilised enzyme derivatives, Organic synthesis, Penicillin G acylase, Stabilised enzyme derivativesAutores:Cristina M. Rosell, Fernandez‐Lafuente R., Guisan J.M.Fuentes:scopus