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A Fuzzy System Classification Approach for QSAR Modeling of αAmylase and α-Glucosidase Inhibitors
ArticleAbstract: Introduction: This report proposes the application of a new Machine Learning algorithm called FuzzyPalabras claves:Anti-diabetic agents, FURIA-C, induction rule, Lda, machine-learning techniques, QSARAutores:Amilkar Puris, Gerardo M. Casañola-Martin, González‐díaz H., Karel Diéguez-Santana, Rasulev B., Rivera-Borroto O.M.Fuentes:googlescopusA new topological descriptors based model for predicting intestinal epithelial transport of drugs in caco-2 cell culture
ArticleAbstract: Purpose: Quantitative Structure-Permeability Relationships (QSPerR) of the intestinal permeability aPalabras claves:Autores:Francisco Torrens, González‐díaz H., Pérez M.A.C., Romero-Zaldivar V., Torrens F., Yovani Marrero-PonceFuentes:googlescopusComputational chemistry comparison of stable/nonstable protein mutants classification models based on 3d and topological indices
ArticleAbstract: In principle, there are different protein structural parameters that can be used in computational chPalabras claves:Protein stability, Protein structure, Spectral moments, topological indicesAutores:González‐díaz H., Podda G., Uriarte E., Yunierkis Perez-CastilloFuentes:googlescopusGene prioritization, communality analysis, networking and metabolic integrated pathway to better understand breast cancer pathogenesis
ArticleAbstract: Consensus strategy was proved to be highly efficient in the recognition of gene-disease association.Palabras claves:Autores:Alejandro Cabrera-Andrade, Andrés López-Cortés, Cesar Paz-y-Miño, Eduardo Tejera, González‐díaz H., Munteanu C.R., Sierra A.P., Stephen Jones Barigye, Yunierkis Perez-CastilloFuentes:googlescopusHP-Lattice QSAR for dynein proteins: Experimental proteomics (2D-electrophoresis, mass spectrometry) and theoretic study of a Leishmania infantum sequence
ArticleAbstract: The toxicity and inefficacy of actual organic drugs against Leishmaniosis justify research projectsPalabras claves:2D-electrophoresis, BLAST, complex networks, Dyneins, HP-Lattice model, Leishmania infantum, Mass spectrometry, Parasites proteomics, QSAR, Sequence alignment, Spectral momentsAutores:Bolas-Fernández F., Chou K.C., Dea-Ayuela M.A., González‐díaz H., Meneses-Marcel A., Ubeira F.M., Yunierkis Perez-CastilloFuentes:googlescopusTowards machine learning discovery of dual antibacterial drug-nanoparticle systems
ArticleAbstract: Artificial Intelligence/Machine Learning (AI/ML) algorithms may speed up the design of DADNP systemsPalabras claves:Autores:González‐díaz H., Karel Diéguez-SantanaFuentes:googlescopusTowards rational nanomaterial design by predicting drug-nanoparticle system interaction vs. bacterial metabolic networks
ArticleAbstract: The emergence of multidrug-resistant (MDR) strains with perturbed metabolic networks (MNs) pushes rePalabras claves:Autores:González‐díaz H., Karel Diéguez-Santana, Rasulev B.Fuentes:googlescopusTrends in Nanoparticles for Leishmania Treatment: A Bibliometric and Network Analysis
ReviewAbstract: Leishmaniasis is a neglected tropical illness with a wide variety of clinical signs ranging from visPalabras claves:Antiprotozoal agents, Bibliometric Analysis, Leishmaniasis treatment, Nanomedicine, Network Analysis, parasite diseasesAutores:Eberto Gutiérrez Morales, Gabriel Mazón-Ortiz, Galo Leonardo Cerda Mejia, González‐díaz H., Karel Diéguez-Santana, Ruso J.M.Fuentes:googleorcidscopusPerturbation-theory machine learning (PTML) multilabel model of the CheMBL dataset of preclinical assays for antisarcoma compounds
ArticleAbstract: Sarcomas are a group of malignant neoplasms of connective tissue with a different etiology than carcPalabras claves:Autores:Alejandro Cabrera-Andrade, Andrés López-Cortés, Arrasate S., Eduardo Tejera, González‐díaz H., Munteanu C.R., Sierra A.P., Yunierkis Perez-CastilloFuentes:googlescopusOncoOmics approaches to reveal essential genes in breast cancer: a panoramic view from pathogenesis to precision medicine
ArticleAbstract: Breast cancer (BC) is the leading cause of cancer-related death among women and the most commonly diPalabras claves:Autores:Alejandro Cabrera-Andrade, Andrés López-Cortés, Cesar Paz-y-Miño, Eduardo Tejera, González‐díaz H., Munteanu C.R., SANTIAGO XAVIER GUERRERO JIJÓN, Sierra A.P., Stephen Jones Barigye, Yunierkis Perez-CastilloFuentes:googlescopus